The UK Biobank Exome Sequencing Consortium (UKB-ESC) is a private-public partnership between the UK Biobank (UKB) and eight biopharmaceutical corporations that may full the sequencing of exomes for all ~500,000 UKB members. Here, we describe the early outcomes from ~200,000 UKB members and the options of this mission that enabled its success. The biopharmaceutical trade has more and more used human genetics to enhance success in drug discovery.
Recognizing the want for large-scale human genetics information, in addition to the distinctive worth of the information entry and contribution phrases of the UKB, the UKB-ESC was fashioned. As a end result, exome information from 200,643 UKB enrollees at the moment are accessible. These information embrace ~10 million exonic variants-a wealthy useful resource of uncommon coding variation that’s notably precious for drug discovery.
The UKB-ESC precompetitive collaboration has additional strengthened tutorial and trade ties and has offered groups with a possibility to work together with and be taught from the wider research neighborhood.
Association of pre-pandemic high-density lipoprotein ldl cholesterol with danger of COVID-19 hospitalisation and demise: The UK Biobank cohort examine
There is rising proof of, and organic plausibility for, elevated ranges of high-density lipoprotein ldl cholesterol (HDL-C) being associated to decrease charges of respiratory illness. We examined whether or not pre-pandemic HDL-C inside the regular vary is related to subsequent COVID-19 hospitalisations and demise. We analysed information on members from UK Biobank, a potential cohort examine, baseline information for which had been collected between 2006 and 2010.
Follow-up for COVID-19 was through hospitalisation data (1845 occasions in 317,306 people) and a nationwide mortality registry (458 deaths in 317,833 people). After controlling for a sequence of confounding elements which included well being behaviours, inflammatory markers, and socio-economic standing, greater ranges of HDL-C had been associated to a decrease danger of later hospitalisation.
The impact was linear (p-value for pattern 0.001), whereby a 0.2 mmol/L enhance in HDL-C was related to a 7% decrease danger (odds ratio; 95% confidence interval: 0.93; 0.90, 0.96). Corresponding relationships for mortality had been markedly weaker, such that statistical significance at standard ranges weren’t obvious for each the linear pattern (p-value 0.25) and the odds ratio per 0.2 mmol/L enhance (0.98; 0.91, 1.05).
While our discovering for HDL-C and hospitalisations for COVID-19 increase the risk that beneficial modification of this ldl cholesterol fraction through life-style modifications or drug intervention could influence upon the danger of the illness, it warrants testing in different research.
Privacy in breast most cancers biobank: Chinese sufferers’ perceptions
Drawing on 40 in-depth interviews with Chinese breast most cancers sufferers who participated in the breast most cancers biobank at a hospital in Beijing, China, this paper explores these sufferers’ perceptions of privateness. The evaluation signifies that these sufferers primarily perceived privateness as informational privateness; they had been involved about the disclosure of contact data, most cancers analysis, and genetic testing outcomes; additional, their views on disclosing completely different varieties of private data had been dynamic and heterogeneous in numerous relationships and contexts, which differs from the stereotypical beliefs of privateness in China.
This paper offers located understanding of why these sufferers had such privateness perceptions and what methods they adopted to deal with their privateness. It then discusses the worldwide similarities and variations in the disclosure of most cancers and genetic testing outcomes.
Establishment of biobank facility at Endocrinology and Metabolism Research Institute of Iran: experiences, challenges, and future outlook
Biobanking as an rising process referring to the growth of pattern storage applied sciences which offer important constructions for conducting research. This paper presents the experiences and challenges confronted whereas establishing the non-communicable ailments (NCDs)-dedicated biobank at Endocrinology and Metabolism Research Institute (EMRI) in Iran, resembling infrastructure, Laboratory Information Management System (LIMS), moral and authorized points, pattern assortment, preservation, and high quality management (QC). NCDs are a significant well being downside round the world and in Iran, which is entry to organic samples are required to understanding and planning to those ailments.
The predominant targets of the EMRI biobank is at present the assortment and storage of organic samples resembling blood, serum, plasma, urine and DNA from sufferers with NCDs together with diabetes mellitus osteoporosis and aged inhabitants primarily based on cohort and cross-sectional research. The biobank of EMRI goals to have a significant influence on the NCDs by supplying organic samples for nationwide and worldwide research initiatives.
Building Research Support Capacity throughout Human Health Biobanks throughout the COVID-19 Pandemic
Human well being biobanks are varieties of research infrastructure that offer biospecimens and related information to researchers, and subsequently juxtapose the actions of scientific care and biomedical research. The self-discipline of biobanking has existed for over 20 years and is supported by a number of worldwide skilled societies and devoted tutorial journals. However, regardless of each rising research demand for human biospecimens, and the development of biobanking as an instructional self-discipline, many particular person biobanks proceed to expertise sustainability challenges.
This commentary will summarize how the COVID-19 pandemic is creating new challenges and alternatives for each the well being biobanking sector and the supporting self-discipline of biobanking. While the challenges for biobanks could also be quite a few and acute, there are alternatives for each particular person biobanks and the self-discipline of biobanking to embrace change such that biobanks can proceed to assist and drive biomedical research.
Dkk-1 Polyclonal Antibody |
|||
| ABP53293-003ml | Abbkine | 0.03ml | 189.6 EUR |
|
Description: A polyclonal antibody for detection of Dkk-1 from Human, Mouse, Rat. This Dkk-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Dkk-1 |
|||
Dkk-1 Polyclonal Antibody |
|||
| ABP53293-01ml | Abbkine | 0.1ml | 346.8 EUR |
|
Description: A polyclonal antibody for detection of Dkk-1 from Human, Mouse, Rat. This Dkk-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Dkk-1 |
|||
Dkk-1 Polyclonal Antibody |
|||
| ABP53293-02ml | Abbkine | 0.2ml | 496.8 EUR |
|
Description: A polyclonal antibody for detection of Dkk-1 from Human, Mouse, Rat. This Dkk-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Dkk-1 |
|||
DKK-1 Recombinant Protein |
|||
| 40-225-0002mg | ProSci | 0.002 mg | 311.1 EUR |
|
Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 expressed in human 293 cells is a 35-40 kDa glycoprotein containing 235 amino-acid residues. |
|||
DKK-1 Recombinant Protein |
|||
| 40-225-001mg | ProSci | 0.01 mg | 437.1 EUR |
|
Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 expressed in human 293 cells is a 35-40 kDa glycoprotein containing 235 amino-acid residues. |
|||
Dkk-1 Polyclonal Antibody |
|||
| 41928-100ul | SAB | 100ul | 302.4 EUR |
Dkk-1 Polyclonal Antibody |
|||
| 41928-50ul | SAB | 50ul | 224.4 EUR |
Dkk-1 Polyclonal Antibody |
|||
| ES4292-100ul | ELK Biotech | 100ul | 334.8 EUR |
|
Description: A Rabbit Polyclonal antibody against Dkk-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
|||
Dkk-1 Polyclonal Antibody |
|||
| ES4292-50ul | ELK Biotech | 50ul | 248.4 EUR |
|
Description: A Rabbit Polyclonal antibody against Dkk-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
|||
Dkk-2 |
|||
| GT15222 | Neuromics | 100 ug | 631.2 EUR |
DKK 1 Recombinant Protein |
|||
| 96-236 | ProSci | 0.1 mg | 752.1 EUR |
|
Description: Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK1 takes part in embryonic development through its inhibition of the WNT signaling pathway, binds to LRP6 with high affinity and prevents the Frizzled-Wnt-LRP6 complex formation in response to Wnts. DKK1 promotes LRP6 internalization and degradation when it forms a ternary complex with the cell surface receptor Kremen.DKK1 not olny functions as a head inducer during development, but also regulates joint remodeling and bone formation, which suggests roles for DKK1 in the pathogenesis of rheumatoid arthritis and multiple myeloma. More recently research reported, DKK1 impacts eye development from a defined developmental time point on, and is critical for lens separation from the surface ectoderm via β-catenin mediated Pdgfrα and E-cadherin expression. |
|||
DKK 1 Recombinant Protein |
|||
| 96-237 | ProSci | 0.025 mg | 619.8 EUR |
|
Description: Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK1 takes part in embryonic development through its inhibition of the WNT signaling pathway, binds to LRP6 with high affinity and prevents the Frizzled-Wnt-LRP6 complex formation in response to Wnts. DKK1 promotes LRP6 internalization and degradation when it forms a ternary complex with the cell surface receptor Kremen.DKK1 not olny functions as a head inducer during development, but also regulates joint remodeling and bone formation, which suggests roles for DKK1 in the pathogenesis of rheumatoid arthritis and multiple myeloma. More recently research reported, DKK1 impacts eye development from a defined developmental time point on, and is critical for lens separation from the surface ectoderm via β-catenin mediated Pdgfrα and E-cadherin expression. |
|||
Human DKK-1 ELISA kit |
|||
| LF-EK50797 | Abfrontier | 1×96T | 777.6 EUR |
DKK-1 ELISA KIT|Human |
|||
| EF000090 | Lifescience Market | 96 Tests | 826.8 EUR |
DKK-1 (CHO-expressed), Mouse |
|||
| HY-P7154 | MedChemExpress | 50ug | 914.4 EUR |
DKK-1 (HEK293-expressed), Human |
|||
| HY-P7155A | MedChemExpress | 50ug | 1011.6 EUR |
Recombinant Human DKK-1 Protein |
|||
| PROTO94907-3 | BosterBio | 10ug | 380.4 EUR |
|
Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 expressed in human 293 cells is a 35-40 kDa glycoprotein containing 235 amino-acid residues. |
|||
Recombinant Mouse Dkk-1 Protein |
|||
| RP01062 | Abclonal | 5 μg | 219.6 EUR |
Dkk-1 Polyclonal Conjugated Antibody |
|||
| C41928 | SAB | 100ul | 476.4 EUR |
Dkk-3 antibody |
|||
| 22898-100ul | SAB | 100ul | 468 EUR |
ELISA kit for Rat DKK-1 |
|||
| EK5668 | SAB | 96 tests | 663.6 EUR |
|
Description: Enzyme-linked immunosorbent assay kit for quantification of Rat DKK-1 in samples from serum, plasma, tissue homogenates and other biological fluids. |
|||
ELISA kit for Human DKK-1 |
|||
| EK5390 | SAB | 96 tests | 663.6 EUR |
|
Description: Enzyme-linked immunosorbent assay kit for quantification of Human DKK-1 in samples from serum, plasma, tissue homogenates and other biological fluids. |
|||
Human DKK-1 PicoKine ELISA Kit |
|||
| EK0867 | BosterBio | 96 wells | 510 EUR |
|
Description: For quantitative detection of human DKK1 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
|||
Human CellExp? DKK-1, Human Recombinant |
|||
| 7132-10 | Biovision | each | 333.6 EUR |
Human CellExp? DKK-1, Human Recombinant |
|||
| 7132-50 | Biovision | each | 1358.4 EUR |
Dkk-3 Recombinant Protein |
|||
| 96-991 | ProSci | 0.05 mg | 651.3 EUR |
|
Description: Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK3 has been proposed as tumour suppressor gene and a marker for tumour blood vessels. DKK3 is the only DKK family member abundantly expressed in normal lung, but silenced by promoter hypermethylation in a large fraction of lung cancer cell lines and lung tumors. Downregulation of DKK3 was correlated with tumor progression and expression of nuclear beta-catenin in lung tumors. Ectopic expression of DKK3 in lung cancer cells with DKK3 hypermethylation induced apoptosis and inhibited TCF-4 activity as well as nuclear accumulation of beta-catenin and expression of TCF-4 targets c-Myc and cyclin D1. DKK3 modulates FGF and Activin/Nodal signaling to regulate mesoderm induction during early Xenopus development, was reported. |
|||
Dkk-3 Polyclonal Antibody |
|||
| ABP54542-003ml | Abbkine | 0.03ml | 189.6 EUR |
|
Description: A polyclonal antibody for detection of Dkk-3 from Human, Mouse. This Dkk-3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Dkk-3 at AA rangle: 80-160 |
|||
Dkk-3 Polyclonal Antibody |
|||
| ABP54542-01ml | Abbkine | 0.1ml | 346.8 EUR |
|
Description: A polyclonal antibody for detection of Dkk-3 from Human, Mouse. This Dkk-3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Dkk-3 at AA rangle: 80-160 |
|||
Dkk-3 Polyclonal Antibody |
|||
| ABP54542-02ml | Abbkine | 0.2ml | 496.8 EUR |
|
Description: A polyclonal antibody for detection of Dkk-3 from Human, Mouse. This Dkk-3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Dkk-3 at AA rangle: 80-160 |
|||
DKK-2 Recombinant Protein |
|||
| 40-651 | ProSci | 2 ug | 311.1 EUR |
|
Description: The dickkopf (DKK)-related protein family is comprised of four central members, DKK-1 - 4, along with the distantly-related DKK family member DKK-11 (Soggy), which is thought to be a descendent of an ancestral DKK-3 precursor due to its unique sequence homology to DKK-3 and no other DKK family member. DKK family members, with the exception of the divergent Soggy, share two conserved cysteine-rich domains and show very little sequence similarity outside of these domains. Playing an important regulatory role in vertebrate development through localized inhibition of Wnt-regulated processes, including anterior-posterior axial patterning, limb development, somitogenesis, and eye formation, DKKs have also been implicated post-developmentally in bone formation, bone disease, cancer, and neurodegenerative diseases. DKK proteins typically play an important regulatory role in the Wnt/β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/β-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/β-catenin signaling cascade. DKK-2 has been shown to both inhibit and enhance canonical Wnt signaling; enhancing Wnt signaling through direct high-affinity binding of DKK-2 to LRP6 during LRP6 overexpression, while inhibiting Wnt signaling and promoting LRP6 internalization through the formation of a ternary complex between DKK-2, LRP6, and Kremen-2. Recombinant Human DKK-2 expressed in CHO cells is a glycoprotein that has a calculated molecular weight of 25.8 kDa and contains 234 amino acid residues. Due to glycosylation, human DKK-2 migrates at an apparent molecular weight of approximately 31-36 kDa by SDS-PAGE analysis under non-reducing conditions. |
|||
DKK-3 Recombinant Protein |
|||
| 40-652 | ProSci | 2 ug | 311.1 EUR |
|
Description: The dickkopf (DKK)-related protein family is comprised of four central members, DKK-1 - 4, along with the distantly-related DKK family member DKK-L1 (Soggy), which is thought to be a descendent of an ancestral DKK-3 precursor due to its unique sequence homology to DKK-3 and no other DKK family member. DKK family members, with the exception of the divergent Soggy, share two conserved cysteine-rich domains and show very little sequence similarity outside of these domains. Playing an important regulatory role in vertebrate development through localized inhibition of Wnt-regulated processes, including anterior-posterior axial patterning, limb development, somitogenesis, and eye formation, DKKs have also been implicated post-developmentally in bone formation, bone disease, cancer, and neurodegenerative diseases. DKK proteins typically play an important regulatory role in the Wnt/β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/β-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/β-catenin signaling cascade. DKK-3 has been shown to potentiate, rather than inhibit, Wnt signaling through interactions with the high-affinity, transmembrane co-receptors Kremen-1 (Krm1) and Kremen-2 (Krm2). Recombinant Human DKK-3 expressed in CHO cells is a glycoprotein that has a calculated molecular weight of 36.3 kDa and contains 329 amino acid residues. Due to glycosylation, Human DKK-3 migrates at an apparent molecular weight of approximately 39-49 kDa by SDS-PAGE analysis under non-reducing conditions. |
|||
Dkk-3 Polyclonal Antibody |
|||
| ES5541-100ul | ELK Biotech | 100ul | 334.8 EUR |
|
Description: A Rabbit Polyclonal antibody against Dkk-3 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA |
|||
Dkk-3 Polyclonal Antibody |
|||
| ES5541-50ul | ELK Biotech | 50ul | 248.4 EUR |
|
Description: A Rabbit Polyclonal antibody against Dkk-3 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA |
|||
Human DKK-1 ELISA kit (4×96T) |
|||
| LF-EK50798 | Abfrontier | 4×96T | 2641.2 EUR |
Nori® Human DKK-1 ELISA Kit |
|||
| GR106268 | Genorise Scientific | 96-well | 461 EUR |
Nori® Mouse DKK-1 ELISA Kit |
|||
| GR117408 | Genorise Scientific | 96-well | 461 EUR |
Nori® Mouse DKK-1 ELISA Kit |
|||
| GR117418 | Genorise Scientific | 96-well | 461 EUR |
Recombinant Human Dickkopf-Related Protein 2/DKK-2 (N-Fc, C-6His) |
|||
| CC49-10ug | Novoprotein | 10ug | 187.2 EUR |
|
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.2. |
|||
Recombinant Human Dickkopf-Related Protein 2/DKK-2 (N-Fc, C-6His) |
|||
| CC49-1mg | Novoprotein | 1mg | 2739.6 EUR |
|
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.2. |
|||
Recombinant Human Dickkopf-Related Protein 2/DKK-2 (N-Fc, C-6His) |
|||
| CC49-500ug | Novoprotein | 500ug | 1935.6 EUR |
|
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.2. |
|||
Recombinant Human Dickkopf-Related Protein 2/DKK-2 (N-Fc, C-6His) |
|||
| CC49-50ug | Novoprotein | 50ug | 442.8 EUR |
|
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.2. |
|||
DKK 3 Recombinant Protein |
|||
| 96-239 | ProSci | 0.2 mg | 821.4 EUR |
|
Description: Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK3 has been proposed as tumour suppressor gene and a marker for tumour blood vessels. DKK3 is the only DKK family member abundantly expressed in normal lung, but silenced by promoter hypermethylation in a large fraction of lung cancer cell lines and lung tumors. Downregulation of DKK3 was correlated with tumor progression and expression of nuclear beta-catenin in lung tumors. Ectopic expression of DKK3 in lung cancer cells with DKK3 hypermethylation induced apoptosis and inhibited TCF-4 activity as well as nuclear accumulation of beta-catenin and expression of TCF-4 targets c-Myc and cyclin D1. DKK3 modulates FGF and Activin/Nodal signaling to regulate mesoderm induction during early Xenopus development, was reported. |
|||
DKK-3 ELISA KIT|Human |
|||
| EF000091 | Lifescience Market | 96 Tests | 826.8 EUR |
Anti-Dkk-1 antibody |
|||
| STJ97257 | St John's Laboratory | 200 µl | 236.4 EUR |
|
Description: Rabbit polyclonal to Dkk-1. |
|||
Anti-Dkk-1 antibody |
|||
| STJ98000 | St John's Laboratory | 100 µl | 280.8 EUR |
|
Description: Mouse monoclonal to Dkk-1. |
|||
Recombinant Human Dkk-3 Protein |
|||
| RP00355 | Abclonal | 10 μg | 196.8 EUR |
Human DKK-1(Dickkopf-related protein 1) ELISA Kit |
|||
| EH0113 | FN Test | 96T | 628.92 EUR |
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml |
|||
Dkk-1 ELISA Kit (Human) : 96 Wells (OKAG00221) |
|||
| OKAG00221 | Aviva Systems Biology | 96 Wells | 715.2 EUR |
|
Description: Description of target: This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.;Species reactivity: Human;Application: ELISA;Assay info: Quantitative Colorimentric Sandwich ELISA;Sensitivity: 63 pg/mL |
|||
Recombinant Human Dkk-3/DKK3 Protein |
|||
| RP00209 | Abclonal | 10 μg | 186 EUR |
Nori® Human DKK-1 ELISA Kit (2 plates) |
|||
| GR106268-2 | Genorise Scientific | 2 x 96-well | 832 EUR |
Human DKK-4 PicoKine ELISA Kit |
|||
| EK0868 | BosterBio | 96 wells | 546 EUR |
|
Description: For Quantitative Detection of human DKK-4 in cell culture supernates, serum and plasma(heparin, EDTA). |
|||
Human DKK-3 PicoKine ELISA Kit |
|||
| EK1323 | BosterBio | 96 wells | 510 EUR |
|
Description: For quantitative detection of human DKK-3 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
|||
DKK-3 ELISA Kit (Human) (OKBB00603) |
|||
| OKBB00603 | Aviva Systems Biology | 96 Wells | 606 EUR |
|
Description: Description of target: Dickkopf-related protein 3 is a protein that in humans is encoded by the DKK3 gene. This gene encodes a protein that is a member of the dickkopf family. It is mapped to 11p15.3. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Members of the Dkk-related family display unique patterns of mRNA expression in human and mouse tissues, and are secreted when expressed in 293T cells. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: <= 10 pg/mL |
|||
Recombinant Dkk-1 Protein (Thr 32-His 266) [His] |
|||
| VAng-1453Lsx-100g | Creative Biolabs | 100 µg | 1215.6 EUR |
|
Description: Human Dkk-1, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1) |
|||
Recombinant Dkk-1 Protein (Thr 32-His 266) [His] |
|||
| VAng-1453Lsx-1mg | Creative Biolabs | 1 mg | 5998.8 EUR |
|
Description: Human Dkk-1, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1) |
|||
Recombinant Dkk-1 Protein (Thr 32-His 272) [His] |
|||
| VAng-1455Lsx-500g | Creative Biolabs | 500 µg | 5338.8 EUR |
|
Description: Mouse Dkk-1, His tag, is expressed in HEK 293 cells. (Uniprot ID: O54908) |
|||
Recombinant Dkk-1 Protein (Thr 32-His 272) [His] |
|||
| VAng-1455Lsx-50g | Creative Biolabs | 50 µg | 1215.6 EUR |
|
Description: Mouse Dkk-1, His tag, is expressed in HEK 293 cells. (Uniprot ID: O54908) |
|||
Recombinant Dkk-1 Protein (Thr 32-His 266) [Strep] |
|||
| VAng-1454Lsx-1mg | Creative Biolabs | 1 mg | 7648.8 EUR |
|
Description: Human Dkk-1, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1) |
|||
Recombinant Dkk-1 Protein (Thr 32-His 266) [Strep] |
|||
| VAng-1454Lsx-250g | Creative Biolabs | 250 µg | 2964 EUR |
|
Description: Human Dkk-1, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1) |
|||
Recombinant Dkk-1 Protein (Thr 32-His 266) [Strep] |
|||
| VAng-1454Lsx-25g | Creative Biolabs | 25 µg | 918 EUR |
|
Description: Human Dkk-1, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1) |
|||
Anti-Dkk-3 antibody |
|||
| STJ92720 | St John's Laboratory | 200 µl | 236.4 EUR |
|
Description: Rabbit polyclonal to Dkk-3. |
|||
Anti-Dkk-3 antibody |
|||
| STJ98001 | St John's Laboratory | 100 µl | 280.8 EUR |
|
Description: Mouse monoclonal to Dkk-3. |
|||
Recombinant Dkk-3 Protein (Pro 23-Ile 349) [His] |
|||
| VAng-1456Lsx-1mg | Creative Biolabs | 1 mg | 6592.8 EUR |
|
Description: Mouse Dkk-3, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_056629.1) |
|||
Recombinant Dkk-3 Protein (Pro 23-Ile 349) [His] |
|||
| VAng-1456Lsx-50g | Creative Biolabs | 50 µg | 1017.6 EUR |
|
Description: Mouse Dkk-3, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_056629.1) |
|||
Recombinant Dkk-3 Protein (Pro 23-Ile 350) [His] |
|||
| VAng-1457Lsx-200g | Creative Biolabs | 200 µg | 1347.6 EUR |
|
Description: Human Dkk-3, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_001018067.1) |
|||
Recombinant Dkk-3 Protein (Pro 23-Ile 350) [His] |
|||
| VAng-1457Lsx-20g | Creative Biolabs | 20 µg | 456 EUR |
|
Description: Human Dkk-3, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_001018067.1) |
|||
Human DKK-3(Dickkopf-related protein 3) ELISA Kit |
|||
| EH0114 | FN Test | 96T | 681.12 EUR |
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 37.5pg/ml |
|||
IGF-1-Fc |
|||
| E13-m003-1 | EnoGene | 10μg | 349.2 EUR |
IGF-1-Fc |
|||
| E13-m003-2 | EnoGene | 50μg | 996 EUR |
Frizzled-1, Fc fusion |
|||
| 71123 | BPS Bioscience | 50 µg | 325 EUR |
|
Description: Secreted frizzled receptor (FZD1)-Fc fusion_x000D_protein and WNT receptor, also known as_x000D_FZD1, GenBank Accession No.BC_051271,_x000D_a.a. 73-253, expressed in a HEK293 cell_x000D_expression system. MW = 46.4 kDa_x000D_(monomer). This protein runs at a higher_x000D_apparent M.W. by SDS-PAGE due to_x000D_glycosylation. |
|||
Contactin-1, FC Chimera |
|||
| PR15072 | Neuromics | 100 ug | 568.8 EUR |
TIE-1 Fc Chimera |
|||
| PR27153 | Neuromics | 2 ug | 229.2 EUR |
Fc |
|||
| EF006811 | Lifescience Market | 96 Tests | 826.8 EUR |
Fc |
|||
| EF006812 | Lifescience Market | 96 Tests | 826.8 EUR |
Fc |
|||
| EF006814 | Lifescience Market | 96 Tests | 826.8 EUR |
Fc |
|||
| EF006815 | Lifescience Market | 96 Tests | 826.8 EUR |
B7-1 (CD80), Fc fusion |
|||
| 71125 | BPS Bioscience | 100 µg | 320 EUR |
|
Description: Human secreted B7-1-Fc fusion protein, also known as CD80. GenBank Accession No. NM_005191, a.a. 35-242 expressed in a HEK293 cell expression system. MW = 50.5 kDa (monomer). This protein runs at a higher M.W. by SDS-PAGE due to glycosylation. |
|||
PD-1, Fc Fusion (Woodchuck) |
|||
| 79314 | BPS Bioscience | 100 µg | 320 EUR |
|
Description: Woodchuck (Groundhog, Marmota monax) secreted programmed cell death 1 (PD-1) also known as, PDCD1, SLEB2, CD279 and HPD-L, GenBank Accession No. HQ403652.1, a.a 25-172, fused at the C-terminus to the Fc portion of Human IgG1, expressed in a HEK293 cell expression system. MW = 43 kDa. This protein runs at a higher M.W. by SDS-PAGE due to glycosylation. |
|||
B7-1 Fc Recombinant Protein |
|||
| 40-693 | ProSci | 20 ug | 311.1 EUR |
|
Description: B7-1 and B7-2 are transmembrane glycoproteins of the immunoglobulin superfamily that are expressed, along with the receptors CD28 and CTLA-4, by antigen-presenting cells, and along with these receptors, constitute crucial co-stimulatory pathways for T and B cell regulatory responses. As members of the B7 family, B7-1 and B7-2 play principal roles in immunity, activating immune response and maintaining immune tolerance through engagement with CD28 and CTLA-4. Co-stimulatory signals generated by B7-1 and B7-2 interactions with CD28 serve to stimulate T cell activation and prevent anergy through the amplification of T cell receptor (TCR) signaling. In contrast, interactions of the ligands with CTLA-4 serves to maintain T cell homeostasis and self-tolerance through the disruption of stimulatory signaling from B7 isoform bound CD28 complexes, and by inducing powerful inhibitory signals in T cells. B7-1 plays an important role in immune response through its amplification and regulation of T cell activity at peripheral inflammation sites. B7-1, like CTLA-4, is, however, only poorly expressed on resting dendritic cells, and its up-regulation is, therefore, considerably delayed upon immune activation. Conversely, B7-2 and CD28 are constitutively expressed by resting hematopoietic and T cells, respectively, and as a result are able to rapidly induce up-regulation upon immune activation, making them critical to the early co-stimulatory singling of immune response. Both B7-1 and B7-2 have been shown to demonstrate co-stimulatory activity in T cell proliferation in vitro and elicit enhanced antitumor immune response in vivo. Recombinant Human B7-1Fc is a homodimeric B7-1 fusion protein, whose monomer contains a total of 441 amino acid residues, consisting of 211 amino acid residues corresponding to the extracellular domain of human B7-1, fused to the Fc portion of human IgG1. The calculated molecular weight of the B7-1 Fc monomer is 50.0 kDa. |
|||
TREM-1-Fc Recombinant Protein |
|||
| 40-697 | ProSci | 10 ug | 311.1 EUR |
|
Description: Triggering receptor expressed on myeloid cells-1 (TREM-1) is a type 1 transmembrane glycoprotein belonging to the immunoglobulin superfamily of cell surface receptors that is constitutively expressed on the surface of monocytes, neutrophils and macrophages. The first identified member of the TREM family of receptors, TREM-1 is a proponent of amplified inflammatory responses triggered by bacterial and fungal infection, and functions in association with the signal transduction adaptor molecule DAP12. TREM-1 activation induces the sustained secretion of proinflammatory chemokines (IL-8 and MCP-1) and cytokines (TNF-α, IL-1β, and IL-6), the respiratory burst and degranulation of neutrophils, the upregulation of adhesion molecules involved in leukocyte extravasation, and tissue degradation. Involvement and increased expression of TREM-1, or soluble TREM-1, in infectious, as well as some non-infectious, inflammatory conditions may highlight the protein’s potential as a possible diagnostic marker in cases of severe inflammation, such as myocardial dysfunction related to severe sepsis and spontaneous preterm labor. TREM-1 involvement in inflammatory response has also been noted as a predictor of both progression and aggression in certain cancers. CHO cell-derived Recombinant Human TREM-1 Fc is a glycosylated, disulfide-linked homodimer of 826 amino acid residues whose monomer consists of the 180-amino-acid length extracellular portion of TREM-1 fused to the 231-amino-acid length Fc portion of human IgG1 by two glycines. The calculated molecular weight of Recombinant Human TREM-1 Fc dimer is 92.6 kDa; however, due to glycosylation, the monomer and dimer migrate at apparent molecular weights of approximately 60-65 kDa and 110-116 kDa by SDS-PAGE analysis under reducing conditions. |
|||
PD-1/PDCD1(Fc fusion) |
|||
| E21-J97 | EnoGene | 10ug | 411.6 EUR |
FC Antibody |
|||
| 48379-100ul | SAB | 100ul | 399.6 EUR |
FC Antibody |
|||
| 48379-50ul | SAB | 50ul | 286.8 EUR |
IgG1, Fc |
|||
| 71456 | BPS Bioscience | 200 µg | 265 EUR |
|
Description: Fc region of human immunoglobulin G1 (IgG1) protein, also known as Il-4, GenBank Accession No. P01857, a.a. 100-330, expressed in an HEK293 cell expression system. MW = 27 kDa. |
|||
IgG4, Fc |
|||
| 71457 | BPS Bioscience | 200 µg | 265 EUR |
|
Description: Fc region of human immunoglobulin G4 (IgG4) protein, a.a. 99-327, Genbank Accession #P01861, expressed in an HEK293 cell expression system. MW = 27 kDa. |
|||
FC 131 |
|||
| B7647-1 | ApexBio | 1 mg | 224.4 EUR |
FC 131 |
|||
| B7647-10 | ApexBio | 10 mg | 1382.4 EUR |
FC 131 |
|||
| B7647-5 | ApexBio | 5 mg | 804 EUR |
SCF-Fc |
|||
| E13-m004-1 | EnoGene | 10μg | 411.6 EUR |
SCF-Fc |
|||
| E13-m004-2 | EnoGene | 50μg | 1308 EUR |
pMac- FC |
|||
| PVT11383 | Lifescience Market | 2 ug | 444 EUR |
Notoginsenoside Fc |
|||
| TBZ2655 | ChemNorm | 20mg | Ask for price |
Recombinant Human TIE-1 Fc Chimera |
|||
| 7-04183 | CHI Scientific | 1µg | Ask for price |
Recombinant Human TIE-1 Fc Chimera |
|||
| 7-04184 | CHI Scientific | 3µg | Ask for price |
Recombinant Human TIE-1 Fc Chimera |
|||
| 7-04185 | CHI Scientific | 100µg | Ask for price |
Recombinant Mouse TIE-1 Fc Chimera |
|||
| 7-04186 | CHI Scientific | 1µg | Ask for price |
Recombinant Mouse TIE-1 Fc Chimera |
|||
| 7-04187 | CHI Scientific | 3µg | Ask for price |
Recombinant Mouse TIE-1 Fc Chimera |
|||
| 7-04188 | CHI Scientific | 100µg | Ask for price |
PD-1 (CD279), Fc fusion (Human) |
|||
| 71106-1 | BPS Bioscience | 100 µg | 345 EUR |
|
Description: Human secreted programmed cell death 1 (PD-1)-Fc fusion protein, also known as, PDCD1, SLEB2, CD279 and HPD-L, GenBank Accession No. NM_005018, a.a 25-167, fused at the C-terminus to the Fc portion of human IgG1, expressed in a HEK293 cell expression system. MW = 42.6 kDa. This protein runs at a higher M.W. by SDS-PAGE due to glycosylation. |
|||
PD-1 (CD279), Fc fusion (Human) |
|||
| 71106-2 | BPS Bioscience | 1 mg | 2755 EUR |
|
Description: Human secreted programmed cell death 1 (PD-1)-Fc fusion protein, also known as, PDCD1, SLEB2, CD279 and HPD-L, GenBank Accession No. NM_005018, a.a 25-167, fused at the C-terminus to the Fc portion of human IgG1, expressed in a HEK293 cell expression system. MW = 42.6 kDa. This protein runs at a higher M.W. by SDS-PAGE due to glycosylation. |
|||
Mouse PD-1 (CD279), Fc fusion |
|||
| 71116 | BPS Bioscience | 100 µg | 335 EUR |
|
Description: Mouse secreted Programmed Cell Death 1_x000D_(PD-1)-Fc fusion protein, also known as_x000D_CD279, PDCD1, and SLEB2, GenBank_x000D_Accession No. NM_008798, a.a. 25-167,_x000D_fused at the C-terminus to the Fc portion of_x000D_mouse IgG2a, expressed in a HEK293 cell_x000D_expression system. MW = 43.2 kDa. Note:_x000D_this protein runs at an apparent higher_x000D_molecular weight due to glycosylation. |
|||
PD-1, Fc Fusion, PE-labeled |
|||
| 71243-1 | BPS Bioscience | 50 µg | 455 EUR |
|
Description: Human secreted programmed cell death 1 (PD-1)-Fc fusion protein, also known as, PDCD1, SLEB2, CD279 and HPD-L, GenBank Accession No. NM_005018, a.a 25-167, fused at the Cterminus to the Fc portion of human IgG1, expressed in a HEK293 cell expression system. This protein runs at a higher M.W. by SDS-PAGE due to glycosylation. The protein was randomly labeled with RPE on accessible lysine residues. |
|||
PD-1, Fc fusion, Avi-Tag |
|||
| 100406 | BPS Bioscience | 100 µg | 320 EUR |
|
Description: Human secreted programmed cell death 1 (PD-1), also known as PDCD1, SLEB2, CD279 and HPD-L, GenBank Accession No. NM_005018, a.a 25-167, fused at the C-terminus to the Fc portion of human IgG1, with C-terminal Avi-tag™ expressed in a HEK293 cell expression system. MW = 44.5 kDa. |
|||
TIE-1 Fc Chimera Protein (Recombinant) |
|||
| 20-abx073607 | Abbexa |
|
|
TIE-1 Fc Chimera Protein (Recombinant) |
|||
| 20-abx073608 | Abbexa |
|
|
PDCD1/PD-1/CD279 (Fc fusion) |
|||
| E21-M81 | EnoGene | 10ug | 411.6 EUR |
VCAM-1/CD106, Fc Chimera, CF |
|||
| PR15087CF | Neuromics | 100 ug | 841.2 EUR |
Human Immunoglobulin G1-Fc (IgG1-Fc) Antibody |
|||
| 34105-05111 | AssayPro | 150 ug | 313.2 EUR |
Human Immunoglobulin G3-Fc (IgG3-Fc) Antibody |
|||
| 34107-05111 | AssayPro | 150 ug | 313.2 EUR |
Human Immunoglobulin G4-Fc (IgG4-Fc) Antibody |
|||
| 34108-05111 | AssayPro | 150 ug | 313.2 EUR |
Human Immunoglobulin G2-Fc (IgG2-Fc) Antibody |
|||
| 34106-05111 | AssayPro | 150 ug | 313.2 EUR |
TIE1-Fc TIE1 Fc Human Recombinant Protein |
|||
| PROTP35590 | BosterBio | Regular: 10ug | 380.4 EUR |
|
Description: Soluble TIE-1 Human Recombinant fused with the Fc part of human IgG1 produced in baculovirus is a homodimeric, glycosylated, polypeptide containing 749 amino acids and having a total molecular mass of 250 kDa. Human TIE-1/Fc monomer has a calculated molecular mass of approximately 105 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 125 kDa protein in SDS-PAGE under reducing conditions.;The TIE1 Fc Chimera is purified by proprietary chromatographic techniques. |
|||
Recombinant Human Mucin-1/MUC-1 (C-Fc) |
|||
| CS58-10ug | Novoprotein | 10ug | 169.2 EUR |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
|||
Recombinant Human Mucin-1/MUC-1 (C-Fc) |
|||
| CS58-1mg | Novoprotein | 1mg | 2008.8 EUR |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
|||
Recombinant Human Mucin-1/MUC-1 (C-Fc) |
|||
| CS58-500ug | Novoprotein | 500ug | 1423.2 EUR |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
|||
Recombinant Human Mucin-1/MUC-1 (C-Fc) |
|||
| CS58-50ug | Novoprotein | 50ug | 363.6 EUR |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
|||
Pig Macrophage Colony-Stimulating Factor 1-IgG1a Fc Region (CSF1-Fc) Fusion Protein |
|||
| abx670323-1mg | Abbexa | 1 mg | 1963.2 EUR |
B7-1 (CD80), Fc fusion, Biotin-labeled |
|||
| 71114-1 | BPS Bioscience | 25 µg | 295 EUR |
|
Description: Human secreted B7-1-Fc fusion protein, also known as CD80, with C-terminal Avi-tag™. GenBank Accession No. NM_005191, a.a 35-242 expressed in a HEK293 cell expression system and enzymatically biotin-labeled using Avi-tag™ technology. MW = 52.5 kDa (monomer). This protein runs at a higher M.W. by SDS-PAGE due to glycosylation. |
|||
B7-1 (CD80), Fc fusion, Biotin-labeled |
|||
| 71114-2 | BPS Bioscience | 50 µg | 435 EUR |
|
Description: Human secreted B7-1-Fc fusion protein, also known as CD80, with C-terminal Avi-tag™. GenBank Accession No. NM_005191, a.a 35-242 expressed in a HEK293 cell expression system and enzymatically biotin-labeled using Avi-tag™ technology. MW = 52.5 kDa (monomer). This protein runs at a higher M.W. by SDS-PAGE due to glycosylation. |
|||
Monkey (M. fascicularis) PD-1, Fc fusion |
|||
| 71158 | BPS Bioscience | 100 µg | 330 EUR |
|
Description: Monkey secreted Programmed Cell Death 1 (PD-1)-Fc fusion protein, also known as CD279, PDCD1, and SLEB2, GenBank Accession No. NM_005018, a.a. 25-167, fused at the C-terminus to the Fc portion of human IgG1, expressed in a HEK293 cell expression system. MW = 42.6 kDa. Note: this protein runs at an apparent higher molecular weight due to glycosylation. |
|||
PD-1 (I126A), Fc fusion, Biotin-labeled |
|||
| 71238-1 | BPS Bioscience | 25 µg | 295 EUR |
|
Description: Human secreted Programmed Cell Death 1_x000D_(PD-1)-Fc fusion protein, also known as_x000D_CD279, PDCD1, and SLEB2, GenBank_x000D_Accession No. NM_014143, amino acids_x000D_25-167 with an I126A mutation, fused at the_x000D_C-terminus with the Fc portion of human_x000D_IgG1, and C-terminal AviTag™, expressed_x000D_in a HEK293 cell expression system and_x000D_enzymatically biotin-labeled using AviTag™_x000D_technology. MW = 44.5 kDa. This protein_x000D_runs at a higher MW by SDS-PAGE due to_x000D_glycosylation. |
|||
PD-1 (I126A), Fc fusion, Biotin-labeled |
|||
| 71238-2 | BPS Bioscience | 50 µg | 435 EUR |
|
Description: Human secreted Programmed Cell Death 1_x000D_(PD-1)-Fc fusion protein, also known as_x000D_CD279, PDCD1, and SLEB2, GenBank_x000D_Accession No. NM_014143, amino acids_x000D_25-167 with an I126A mutation, fused at the_x000D_C-terminus with the Fc portion of human_x000D_IgG1, and C-terminal AviTag™, expressed_x000D_in a HEK293 cell expression system and_x000D_enzymatically biotin-labeled using AviTag™_x000D_technology. MW = 44.5 kDa. This protein_x000D_runs at a higher MW by SDS-PAGE due to_x000D_glycosylation. |
|||
PD-1, Fc Fusion, PE-labeled (Human) |
|||
| 71243-2 | BPS Bioscience | 500 µg_x000D_ | 4315 EUR |
|
Description: Human secreted programmed cell death 1 (PD-1)-Fc fusion protein, also known as PE-labeled PD-1, PDCD1, SLEB2, CD279 and HPD-L, GenBank Accession No. NM_005018, a.a 25-167, fused at the Cterminus to the Fc portion of human IgG1, expressed in a HEK293 cell expression system. This protein runs at a higher M.W. by SDS-PAGE due to glycosylation. The protein was randomly labeled with RPE on accessible lysine residues. |
|||
PD-1 (K78A), Fc fusion, Biotin-labeled |
|||
| 71244-1 | BPS Bioscience | 25 µg | 295 EUR |
|
Description: Human secreted Programmed Cell Death 1_x000D_(PD-1)-Fc fusion protein, also known as_x000D_CD279, PDCD1, and SLEB2, GenBank_x000D_Accession No. NM_014143, a.a. 25-167_x000D_with a K78A mutation, fused at the Cterminus_x000D_with the Fc portion of human IgG1,_x000D_and C-terminal AviTag™, expressed in a_x000D_HEK293 cell expression system and_x000D_enzymatically biotin-labeled using AviTag™_x000D_technology. MW = 44.5 kDa. This protein_x000D_runs at a higher MW by SDS-PAGE due to_x000D_glycosylation. |
|||
PD-1 (K78A), Fc fusion, Biotin-labeled |
|||
| 71244-2 | BPS Bioscience | 50 µg | 435 EUR |
|
Description: Human secreted Programmed Cell Death 1_x000D_(PD-1)-Fc fusion protein, also known as_x000D_CD279, PDCD1, and SLEB2, GenBank_x000D_Accession No. NM_014143, a.a. 25-167_x000D_with a K78A mutation, fused at the Cterminus_x000D_with the Fc portion of human IgG1,_x000D_and C-terminal AviTag™, expressed in a_x000D_HEK293 cell expression system and_x000D_enzymatically biotin-labeled using AviTag™_x000D_technology. MW = 44.5 kDa. This protein_x000D_runs at a higher MW by SDS-PAGE due to_x000D_glycosylation. |
|||
PD-1 (I134A), Fc fusion, Biotin-labeled |
|||
| 71245-1 | BPS Bioscience | 25 µg | 295 EUR |
|
Description: Human secreted Programmed Cell Death 1_x000D_(PD-1)-Fc fusion protein, also known as_x000D_CD279, PDCD1, and SLEB2, GenBank_x000D_Accession No. NM_014143, a.a. 25-167_x000D_with an I134A mutation, fused at the Cterminus_x000D_with the Fc portion of human IgG1,_x000D_and C-terminal AviTag™, expressed in a_x000D_HEK293 cell expression system and_x000D_enzymatically biotin-labeled using AviTag™_x000D_technology. MW = 44.5 kDa. This protein_x000D_runs at a higher MW by SDS-PAGE due to_x000D_glycosylation. |
|||
PD-1 (I134A), Fc fusion, Biotin-labeled |
|||
| 71245-2 | BPS Bioscience | 50 µg | 435 EUR |
|
Description: Human secreted Programmed Cell Death 1_x000D_(PD-1)-Fc fusion protein, also known as_x000D_CD279, PDCD1, and SLEB2, GenBank_x000D_Accession No. NM_014143, a.a. 25-167_x000D_with an I134A mutation, fused at the Cterminus_x000D_with the Fc portion of human IgG1,_x000D_and C-terminal AviTag™, expressed in a_x000D_HEK293 cell expression system and_x000D_enzymatically biotin-labeled using AviTag™_x000D_technology. MW = 44.5 kDa. This protein_x000D_runs at a higher MW by SDS-PAGE due to_x000D_glycosylation. |
|||
PD-1 (P130A), Fc fusion, Biotin-labeled |
|||
| 71246-1 | BPS Bioscience | 25 µg | 295 EUR |
|
Description: Human secreted Programmed Cell Death 1_x000D_(PD-1)-Fc fusion protein, also known as_x000D_CD279, PDCD1, and SLEB2, GenBank_x000D_Accession No. NM_014143, a.a. 25-167_x000D_with an P130A mutation, fused at the Cterminus_x000D_with the Fc portion of human IgG1,_x000D_and C-terminal AviTag™, expressed in a_x000D_HEK293 cell expression system and_x000D_enzymatically biotin-labeled using AviTag™_x000D_technology. MW = 44.5 kDa. This protein_x000D_runs at a higher MW by SDS-PAGE due to_x000D_glycosylation. |
|||
PD-1 (P130A), Fc fusion, Biotin-labeled |
|||
| 71246-2 | BPS Bioscience | 50 µg | 435 EUR |
|
Description: Human secreted Programmed Cell Death 1_x000D_(PD-1)-Fc fusion protein, also known as_x000D_CD279, PDCD1, and SLEB2, GenBank_x000D_Accession No. NM_014143, a.a. 25-167_x000D_with an P130A mutation, fused at the Cterminus_x000D_with the Fc portion of human IgG1,_x000D_and C-terminal AviTag™, expressed in a_x000D_HEK293 cell expression system and_x000D_enzymatically biotin-labeled using AviTag™_x000D_technology. MW = 44.5 kDa. This protein_x000D_runs at a higher MW by SDS-PAGE due to_x000D_glycosylation. |
|||
PD-1 (E136A), Fc fusion, Biotin-labeled |
|||
| 71247-1 | BPS Bioscience | 25 µg | 295 EUR |
|
Description: Human secreted Programmed Cell Death 1_x000D_(PD-1)-Fc fusion protein, also known as_x000D_CD279, PDCD1, and SLEB2, GenBank_x000D_Accession No. NM_014143, a.a. 25-167_x000D_with an E136A mutation, fused at the Cterminus_x000D_with the Fc portion of human IgG1,_x000D_and C-terminal AviTag™, expressed in a_x000D_HEK293 cell expression system and_x000D_enzymatically biotin-labeled using AviTag™_x000D_technology. MW = 44.5 kDa. This protein_x000D_runs at a higher MW by SDS-PAGE due to_x000D_glycosylation. |
|||
PD-1 (E136A), Fc fusion, Biotin-labeled |
|||
| 71247-2 | BPS Bioscience | 50 µg | 435 EUR |
|
Description: Human secreted Programmed Cell Death 1_x000D_(PD-1)-Fc fusion protein, also known as_x000D_CD279, PDCD1, and SLEB2, GenBank_x000D_Accession No. NM_014143, a.a. 25-167_x000D_with an E136A mutation, fused at the Cterminus_x000D_with the Fc portion of human IgG1,_x000D_and C-terminal AviTag™, expressed in a_x000D_HEK293 cell expression system and_x000D_enzymatically biotin-labeled using AviTag™_x000D_technology. MW = 44.5 kDa. This protein_x000D_runs at a higher MW by SDS-PAGE due to_x000D_glycosylation. |
|||
PD-1 (L128A), Fc fusion, Biotin-labeled |
|||
| 71248-1 | BPS Bioscience | 25 µg | 295 EUR |
|
Description: Human secreted Programmed Cell Death 1_x000D_(PD-1)-Fc fusion protein, also known as_x000D_CD279, PDCD1, and SLEB2, GenBank_x000D_Accession No. NM_014143, a.a. 25-167_x000D_with an L128A mutation, fused at the Cterminus_x000D_with the Fc portion of human IgG1,_x000D_and C-terminal AviTag™, expressed in a_x000D_HEK293 cell expression system and_x000D_enzymatically biotin-labeled using AviTag™_x000D_technology. MW = 44.5 kDa. This protein_x000D_runs at a higher MW by SDS-PAGE due to_x000D_glycosylation. |
|||
PD-1 (L128A), Fc fusion, Biotin-labeled |
|||
| 71248-2 | BPS Bioscience | 50 µg | 435 EUR |
|
Description: Human secreted Programmed Cell Death 1_x000D_(PD-1)-Fc fusion protein, also known as_x000D_CD279, PDCD1, and SLEB2, GenBank_x000D_Accession No. NM_014143, a.a. 25-167_x000D_with an L128A mutation, fused at the Cterminus_x000D_with the Fc portion of human IgG1,_x000D_and C-terminal AviTag™, expressed in a_x000D_HEK293 cell expression system and_x000D_enzymatically biotin-labeled using AviTag™_x000D_technology. MW = 44.5 kDa. This protein_x000D_runs at a higher MW by SDS-PAGE due to_x000D_glycosylation. |
|||
Mouse PD-1, Fc fusion, PE-labeled |
|||
| 71267 | BPS Bioscience | 50 µg | 435 EUR |
|
Description: Mouse secreted programmed cell death 1 (PD-1)-Fc fusion protein, also known as, PDCD1, SLEB2, CD279 and HPD-L, GenBank Accession No. NM_008798, a.a 25-167, fused at the C-terminus to the Fc portion of mouse IgG1, expressed in a HEK293 cell expression system. MW = 43 kDa. This protein runs at a higher M.W. by SDS-PAGE due to glycosylation. The protein was randomly labeled with RPE on accessible lysine residues. |
|||
PD-1, Fc Fusion (IgG1), Eu-labeled |
|||
| 79011 | BPS Bioscience | 100 µg | 325 EUR |
|
Description: Human secreted programmed_x000D_ cell death 1 (PD-1) also known as PDCD1,_x000D_ SLEB2, CD279 and HPD-L, GenBank_x000D_ Accession No. NM_005018, a.a 25-167,_x000D_ fused at the C-terminus to the Fc portion of_x000D_ human IgG1, Eu-labeled, expressed in a_x000D_ HEK293 cell expression system. MW = 43_x000D_ kDa. |
|||
Recombinant Cynomolgus CD80/B7-1 (C-Fc) |
|||
| CP60-10ug | Novoprotein | 10ug | 128.4 EUR |
|
Description: Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 100 mM Glycine, pH7.5. |
|||
Recombinant Cynomolgus CD80/B7-1 (C-Fc) |
|||
| CP60-1mg | Novoprotein | 1mg | 2496 EUR |
|
Description: Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 100 mM Glycine, pH7.5. |
|||
Recombinant Cynomolgus CD80/B7-1 (C-Fc) |
|||
| CP60-500ug | Novoprotein | 500ug | 1765.2 EUR |
|
Description: Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 100 mM Glycine, pH7.5. |
|||
Recombinant Cynomolgus CD80/B7-1 (C-Fc) |
|||
| CP60-50ug | Novoprotein | 50ug | 267.6 EUR |
|
Description: Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 100 mM Glycine, pH7.5. |
|||
Recombinant Mouse B7-1/CD80 (C-Fc) |
|||
| CK87-10ug | Novoprotein | 10ug | 96 EUR |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
|||
Recombinant Mouse B7-1/CD80 (C-Fc) |
|||
| CK87-1mg | Novoprotein | 1mg | 1216.8 EUR |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
|||
Recombinant Mouse B7-1/CD80 (C-Fc) |
|||
| CK87-500ug | Novoprotein | 500ug | 790.8 EUR |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
|||
Recombinant Mouse B7-1/CD80 (C-Fc) |
|||
| CK87-50ug | Novoprotein | 50ug | 169.2 EUR |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
|||
Recombinant Mouse Frizzled 1/FZD1 (C-Fc) |
|||
| CM61-10ug | Novoprotein | 10ug | 151.2 EUR |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
|||
Recombinant Mouse Frizzled 1/FZD1 (C-Fc) |
|||
| CM61-1mg | Novoprotein | 1mg | 2252.4 EUR |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
|||
Recombinant Mouse Frizzled 1/FZD1 (C-Fc) |
|||
| CM61-500ug | Novoprotein | 500ug | 1593.6 EUR |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
|||
Recombinant Mouse Frizzled 1/FZD1 (C-Fc) |
|||
| CM61-50ug | Novoprotein | 50ug | 278.4 EUR |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
|||
Fc Receptor-Like Protein 1 (FCRL1) Antibody |
|||
| abx030308-400ul | Abbexa | 400 ul | 627.6 EUR |
Fc Receptor-Like Protein 1 (FCRL1) Antibody |
|||
| abx030308-80l | Abbexa | 80 µl | 343.2 EUR |
Fc Receptor-Like Protein 1 (FCRL1) Antibody |
|||
| abx432683-200ul | Abbexa | 200 ul | 460.8 EUR |
Fc Receptor-Like Protein 1 (FCRL1) Antibody |
|||
| abx432684-200ul | Abbexa | 200 ul | 460.8 EUR |
Recombinant Human TREML1/TLT-1 (C-Fc) |
|||
| CX07-10ug | Novoprotein | 10ug | 175.2 EUR |
|
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
|||
Recombinant Human TREML1/TLT-1 (C-Fc) |
|||
| CX07-1mg | Novoprotein | 1mg | 2739.6 EUR |
|
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
|||
Recombinant Human TREML1/TLT-1 (C-Fc) |
|||
| CX07-500ug | Novoprotein | 500ug | 1935.6 EUR |
|
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
|||
Recombinant Human TREML1/TLT-1 (C-Fc) |
|||
| CX07-50ug | Novoprotein | 50ug | 363.6 EUR |
|
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
|||
PD-1, Fc Chimera (CHO-expressed), Human |
|||
| HY-P7395 | MedChemExpress | 50ug | 321.6 EUR |
Recombinant (Sf9) Human TIE-1 Fc Chimera |
|||
| RP-703 | Alpha Diagnostics | 10 ug | 343.2 EUR |
OPG-Fc Osteoprotegerin Human Recombinant Protein /Fc Chimera |
|||
| PROTO00300-1 | BosterBio | Regular: 50ug | 380.4 EUR |
|
Description: Recombinant OPG produced in yeast contains 2x412 amino acid residues, including 180 residues from mature OPG (a.a 22-201) and 232 residues from the Fc protein of human IgG1, and has a calculated molecular mass of 109.6kDa. |
|||
TIE1-Fc TIE1 Fc Chimera Mouse Recombinant Protein |
|||
| PROTQ06806 | BosterBio | Regular: 10ug | 380.4 EUR |
|
Description: Soluble TIE-1 Mouse Recombinant fused with the Fc part of human IgG1 produced in CHO cells is a glycosylated disulfide-linked homodimeric polypeptide chain containing amino acids 23-749 and having a total molecular mass of 260kDa. The Mouse TIE-1/Fc monomer has a calculated molecular mass of approximately 105kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 130kDa protein in SDS-PAGE under reducing conditions.;The TIE1 Fc Chimera is purified by proprietary chromatographic techniques. |
|||
Human IgG Fc |
|||
| 65R-1006 | Fitzgerald | 1 mg | 536.4 EUR |
|
Description: Human IgG Fc Fragment (FITC) |
|||
CD28, Fc fusion |
|||
| 71113 | BPS Bioscience | 200 µg | 320 EUR |
|
Description: Human secreted CD28-Fc fusion protein, also known as TP44, GenBank Accession No. NM_006139, a.a 19-152, expressed in a HEK293 cell expression system. MW = 41.4 kDa (monomer). This protein runs at a higher M.W. by SDS-PAGE due to glycosylation. |
|||
HVEM, Fc fusion |
|||
| 71142 | BPS Bioscience | 100 µg | 295 EUR |
|
Description: Human herpesvirus entry mediator A, also known as HVEM, TNFRSF14, CD270, and HVEA, GenBank Accession No. NM_003820, a.a. 37-202 fused to human IgG1 Fc, expressed in a HEK293 cell expression system. MW = 44.2 kDa. This protein runs at a higher M.W. by SDSPAGE due to glycosylation. |
|||
CD40, Fc fusion |
|||
| 71174 | BPS Bioscience | 100 µg | 250 EUR |
|
Description: Human secreted CD40, Fc fusion protein, also known as Tumor Necrosis Factor Receptor Superfamily Member 5, TNFRSF5, and Bp50, GenBank Accession No. NM_001250, a.a. 21-193 expressed in a HEK293 cell expression system. MW = 45.9 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation. |
|||
CD27, Fc fusion |
|||
| 71176 | BPS Bioscience | 100 µg | 320 EUR |
|
Description: Human secreted CD27, Fc fusion protein, also known as Tumor Necrosis Factor Receptor Superfamily Member 7, TNFRSF7, and T14, GenBank Accession No. NM_001242, a.a. 21-192 expressed in a HEK293 cell expression system. MW = 45.8 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation. |
|||
CD47, Fc fusion |
|||
| 71177 | BPS Bioscience | 100 µg | 325 EUR |
|
Description: Human CD47, Fc fusion protein, also known as leukocyte surface antigen CD47, Rh-related antigen, integrin-associated protein, antigenic surface determinant protein OA3, antigen identified by monoclonal antibody 1D8, IAP, and MER6. GenBank Accession No. NM_001777, a.a. 19-139 expressed in a HEK293 cell expression system. MW = 40 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation. |
|||
TIGIT, Fc fusion |
|||
| 71186 | BPS Bioscience | 100 µg | 320 EUR |
|
Description: Human T-cell immunoreceptor with Ig and_x000D_ITIM domains (TIGIT), also known as V-set_x000D_and immunoglobulin domain-containing_x000D_protein 9, VSIG9, V-set and transmembrane_x000D_domain-containing protein 3, and VSTM3,_x000D_GenBank Accession No. NM_173799, a.a._x000D_22-141 fused to Fc region of human IgG,_x000D_expressed in a HEK293 cell expression_x000D_system. MW = 39.7 kDa. This protein runs_x000D_at a higher MW by SDS-PAGE due to_x000D_glycosylation. |
|||
We will subsequently describe quite a few sensible steps that particular person biobanks and/or the self-discipline of biobanking can take to outlive and probably thrive in response to the COVID-19 pandemic.