The UK Biobank Exome Sequencing Consortium (UKB-ESC) is a private-public partnership between the UK Biobank (UKB) and eight biopharmaceutical corporations that may full the sequencing of exomes for all ~500,000 UKB members. Here, we describe the early outcomes from ~200,000 UKB members and the options of this mission that enabled its success. The biopharmaceutical trade has more and more used human genetics to enhance success in drug discovery.
Recognizing the want for large-scale human genetics information, in addition to the distinctive worth of the information entry and contribution phrases of the UKB, the UKB-ESC was fashioned. As a end result, exome information from 200,643 UKB enrollees at the moment are accessible. These information embrace ~10 million exonic variants-a wealthy useful resource of uncommon coding variation that’s notably precious for drug discovery.
The UKB-ESC precompetitive collaboration has additional strengthened tutorial and trade ties and has offered groups with a possibility to work together with and be taught from the wider research neighborhood.
Association of pre-pandemic high-density lipoprotein ldl cholesterol with danger of COVID-19 hospitalisation and demise: The UK Biobank cohort examine
There is rising proof of, and organic plausibility for, elevated ranges of high-density lipoprotein ldl cholesterol (HDL-C) being associated to decrease charges of respiratory illness. We examined whether or not pre-pandemic HDL-C inside the regular vary is related to subsequent COVID-19 hospitalisations and demise. We analysed information on members from UK Biobank, a potential cohort examine, baseline information for which had been collected between 2006 and 2010.
Follow-up for COVID-19 was through hospitalisation data (1845 occasions in 317,306 people) and a nationwide mortality registry (458 deaths in 317,833 people). After controlling for a sequence of confounding elements which included well being behaviours, inflammatory markers, and socio-economic standing, greater ranges of HDL-C had been associated to a decrease danger of later hospitalisation.
The impact was linear (p-value for pattern 0.001), whereby a 0.2 mmol/L enhance in HDL-C was related to a 7% decrease danger (odds ratio; 95% confidence interval: 0.93; 0.90, 0.96). Corresponding relationships for mortality had been markedly weaker, such that statistical significance at standard ranges weren’t obvious for each the linear pattern (p-value 0.25) and the odds ratio per 0.2 mmol/L enhance (0.98; 0.91, 1.05).
While our discovering for HDL-C and hospitalisations for COVID-19 increase the risk that beneficial modification of this ldl cholesterol fraction through life-style modifications or drug intervention could influence upon the danger of the illness, it warrants testing in different research.
Privacy in breast most cancers biobank: Chinese sufferers’ perceptions
Drawing on 40 in-depth interviews with Chinese breast most cancers sufferers who participated in the breast most cancers biobank at a hospital in Beijing, China, this paper explores these sufferers’ perceptions of privateness. The evaluation signifies that these sufferers primarily perceived privateness as informational privateness; they had been involved about the disclosure of contact data, most cancers analysis, and genetic testing outcomes; additional, their views on disclosing completely different varieties of private data had been dynamic and heterogeneous in numerous relationships and contexts, which differs from the stereotypical beliefs of privateness in China.
This paper offers located understanding of why these sufferers had such privateness perceptions and what methods they adopted to deal with their privateness. It then discusses the worldwide similarities and variations in the disclosure of most cancers and genetic testing outcomes.
Establishment of biobank facility at Endocrinology and Metabolism Research Institute of Iran: experiences, challenges, and future outlook
Biobanking as an rising process referring to the growth of pattern storage applied sciences which offer important constructions for conducting research. This paper presents the experiences and challenges confronted whereas establishing the non-communicable ailments (NCDs)-dedicated biobank at Endocrinology and Metabolism Research Institute (EMRI) in Iran, resembling infrastructure, Laboratory Information Management System (LIMS), moral and authorized points, pattern assortment, preservation, and high quality management (QC). NCDs are a significant well being downside round the world and in Iran, which is entry to organic samples are required to understanding and planning to those ailments.
The predominant targets of the EMRI biobank is at present the assortment and storage of organic samples resembling blood, serum, plasma, urine and DNA from sufferers with NCDs together with diabetes mellitus osteoporosis and aged inhabitants primarily based on cohort and cross-sectional research. The biobank of EMRI goals to have a significant influence on the NCDs by supplying organic samples for nationwide and worldwide research initiatives.
Building Research Support Capacity throughout Human Health Biobanks throughout the COVID-19 Pandemic
Human well being biobanks are varieties of research infrastructure that offer biospecimens and related information to researchers, and subsequently juxtapose the actions of scientific care and biomedical research. The self-discipline of biobanking has existed for over 20 years and is supported by a number of worldwide skilled societies and devoted tutorial journals. However, regardless of each rising research demand for human biospecimens, and the development of biobanking as an instructional self-discipline, many particular person biobanks proceed to expertise sustainability challenges.
This commentary will summarize how the COVID-19 pandemic is creating new challenges and alternatives for each the well being biobanking sector and the supporting self-discipline of biobanking. While the challenges for biobanks could also be quite a few and acute, there are alternatives for each particular person biobanks and the self-discipline of biobanking to embrace change such that biobanks can proceed to assist and drive biomedical research.
Recombinant Dkk-1 Protein (Thr 32-His 266) [Fc] |
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| VAng-1451Lsx-1mg | Creative Biolabs | 1 mg | 5668.8 EUR |
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Description: Human Dkk-1, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1) |
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Human Dkk-1 |
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| MBS691712-0002mg | MyBiosource | 0.002mg | 300 EUR |
Human Dkk-1 |
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| MBS691712-001mg | MyBiosource | 0.01mg | 450 EUR |
Human Dkk-1 |
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| MBS691712-5x001mg | MyBiosource | 5x0.01mg | 1725 EUR |
Human Dkk-1 |
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| MBS692271-0005mg | MyBiosource | 0.005mg | 250 EUR |
Human Dkk-1 |
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| MBS692271-002mg | MyBiosource | 0.02mg | 360 EUR |
Human Dkk-1 |
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| MBS692271-5x002mg | MyBiosource | 5x0.02mg | 1325 EUR |
DKK-1 Antibody |
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| F51803-0.4ML | NSJ Bioreagents | 0.4 ml | 322.15 EUR |
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Description: DKK-1 is a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK-1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. |
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Dkk-1 Antibody |
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| C30180-100ul | Assay Biotech | 100μl | 217 EUR |
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Description: Dkk-1 Rabbit Polyclonal Antibody |
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Dkk-1 Antibody |
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| C30180-50ul | Assay Biotech | 50μl | 143.5 EUR |
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Description: Dkk-1 Rabbit Polyclonal Antibody |
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Recombinant Human Dickkopf-Related Protein 1/DKK-1 (C-Fc) |
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| PKSH034024-10ug | Elabscience Biotech | 10ug | 100 EUR |
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Description: Human |
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Recombinant Human Dickkopf-Related Protein 1/DKK-1 (C-Fc) |
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| PKSH034024-50ug | Elabscience Biotech | 50ug | 300 EUR |
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Description: Human |
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Recombinant Human Dickkopf-Related Protein 1/DKK-1 (C-Fc) |
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| MBS2569207-001mg | MyBiosource | 0.01mg | 160 EUR |
Recombinant Human Dickkopf-Related Protein 1/DKK-1 (C-Fc) |
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| MBS2569207-005mg | MyBiosource | 0.05mg | 310 EUR |
Recombinant Human Dickkopf-Related Protein 1/DKK-1 (C-Fc) |
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| MBS2569207-5x005mg | MyBiosource | 5x0.05mg | 1395 EUR |
Recombinant Dkk-1 Protein (Thr 32-His 266) [Fc] [Avi] |
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| VAng-1452Lsx-200g | Creative Biolabs | 200 µg | 4612.8 EUR |
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Description: Biotinylated Human Dkk-1, Fc tag and Avi tag, is expressed in HEK 293 cells. (Uniprot ID: O94907-1) |
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Recombinant Dkk-1 Protein (Thr 32-His 266) [Fc] [Avi] |
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| VAng-1452Lsx-25g | Creative Biolabs | 25 µg | 1215.6 EUR |
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Description: Biotinylated Human Dkk-1, Fc tag and Avi tag, is expressed in HEK 293 cells. (Uniprot ID: O94907-1) |
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Dkk-1 Rabbit pAb |
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| E2251891 | EnoGene | 100ul | 225 EUR |
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Description: Available in various conjugation types. |
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DKK-1 Rabbit pAb |
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| MBS8540496-01mL | MyBiosource | 0.1mL | 305 EUR |
DKK-1 Rabbit pAb |
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| MBS8540496-01mLAF405L | MyBiosource | 0.1mL(AF405L) | 565 EUR |
DKK-1 Rabbit pAb |
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| MBS8540496-01mLAF405S | MyBiosource | 0.1mL(AF405S) | 565 EUR |
DKK-1 Rabbit pAb |
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| MBS8540496-01mLAF610 | MyBiosource | 0.1mL(AF610) | 565 EUR |
DKK-1 Rabbit pAb |
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| MBS8540496-01mLAF635 | MyBiosource | 0.1mL(AF635) | 565 EUR |
Dkk-1 (mouse), (recombinant) |
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| MBS566756-0005mg | MyBiosource | 0.005mg | 330 EUR |
Dkk-1 (mouse), (recombinant) |
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| MBS566756-5x0005mg | MyBiosource | 5x0.005mg | 1420 EUR |
Dkk-1 Recombinant Protein |
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| 96-861 | ProSci | 0.1 mg | 651.3 EUR |
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Description: Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK1 takes part in embryonic development through its inhibition of the WNT signaling pathway, binds to LRP6 with high affinity and prevents the Frizzled-Wnt-LRP6 complex formation in response to Wnts. DKK1 promotes LRP6 internalization and degradation when it forms a ternary complex with the cell surface receptor Kremen.DKK1 not olny functions as a head inducer during development, but also regulates joint remodeling and bone formation, which suggests roles for DKK1 in the pathogenesis of rheumatoid arthritis and multiple myeloma. More recently research reported, DKK1 impacts eye development from a defined developmental time point on, and is critical for lens separation from the surface ectoderm via beta-catenin mediated Pdgfralpha and E-cadherin expression. |
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Dkk-1 Recombinant Protein |
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| 96-990 | ProSci | 0.05 mg | 714.3 EUR |
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Description: Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK1 takes part in embryonic development through its inhibition of the WNT signaling pathway, binds to LRP6 with high affinity and prevents the Frizzled-Wnt-LRP6 complex formation in response to Wnts. DKK1 promotes LRP6 internalization and degradation when it forms a ternary complex with the cell surface receptor Kremen.DKK1 not olny functions as a head inducer during development, but also regulates joint remodeling and bone formation, which suggests roles for DKK1 in the pathogenesis of rheumatoid arthritis and multiple myeloma. More recently research reported, DKK1 impacts eye development from a defined developmental time point on, and is critical for lens separation from the surface ectoderm via beta-catenin mediated Pdgfralpha and E-cadherin expression. |
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Dkk-1 Polyclonal Antibody |
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| ABP53293-003ml | Abbkine | 0.03ml | 189.6 EUR |
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Description: A polyclonal antibody for detection of Dkk-1 from Human, Mouse, Rat. This Dkk-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Dkk-1 |
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Dkk-1 Polyclonal Antibody |
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| ABP53293-01ml | Abbkine | 0.1ml | 346.8 EUR |
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Description: A polyclonal antibody for detection of Dkk-1 from Human, Mouse, Rat. This Dkk-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Dkk-1 |
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Dkk-1 Polyclonal Antibody |
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| ABP53293-02ml | Abbkine | 0.2ml | 496.8 EUR |
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Description: A polyclonal antibody for detection of Dkk-1 from Human, Mouse, Rat. This Dkk-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Dkk-1 |
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Dkk-1 Polyclonal Antibody |
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| 41928-100ul | SAB | 100ul | 302.4 EUR |
Dkk-1 Polyclonal Antibody |
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| 41928-50ul | SAB | 50ul | 224.4 EUR |
DKK-1 Recombinant Protein |
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| 40-225-0002mg | ProSci | 0.002 mg | 311.1 EUR |
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Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 expressed in human 293 cells is a 35-40 kDa glycoprotein containing 235 amino-acid residues. |
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DKK-1 Recombinant Protein |
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| 40-225-001mg | ProSci | 0.01 mg | 437.1 EUR |
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Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 expressed in human 293 cells is a 35-40 kDa glycoprotein containing 235 amino-acid residues. |
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Dkk-1 Polyclonal Antibody |
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| E041928 | EnoGene | 100μg/100μl | 255 EUR |
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Description: Available in various conjugation types. |
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Dkk-1 Polyclonal Antibody |
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| E20-75562 | EnoGene | 100ug | 225 EUR |
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Description: Available in various conjugation types. |
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Dkk-1 Monoclonal Antibody |
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| BT-MCA0444-100ul | Jiaxing Korain Biotech Ltd (BT Labs) | 100ul | Ask for price |
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Description: This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. |
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Dkk-1 Monoclonal Antibody |
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| BT-MCA0444-50ul | Jiaxing Korain Biotech Ltd (BT Labs) | 50ul | Ask for price |
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Description: This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. |
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Dkk-1 Polyclonal Antibody |
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| E44H07004 | EnoGene | 100ul | 255 EUR |
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Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
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Dkk-1 Polyclonal Antibody |
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| BT-AP02622-100ul | Jiaxing Korain Biotech Ltd (BT Labs) | 100ul | Ask for price |
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Description: DKK1 encodes dickkopf WNT signaling pathway inhibitor 1 that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. |
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Dkk-1 Polyclonal Antibody |
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| BT-AP02622-20ul | Jiaxing Korain Biotech Ltd (BT Labs) | 20ul | Ask for price |
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Description: DKK1 encodes dickkopf WNT signaling pathway inhibitor 1 that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. |
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Dkk-1 Polyclonal Antibody |
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| BT-AP02622-50ul | Jiaxing Korain Biotech Ltd (BT Labs) | 50ul | Ask for price |
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Description: DKK1 encodes dickkopf WNT signaling pathway inhibitor 1 that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. |
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Dkk-1 Polyclonal Antibody |
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| MBS9246178-01mL | MyBiosource | 0.1mL | 415 EUR |
Dkk-1 Polyclonal Antibody |
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| MBS9246178-5x01mL | MyBiosource | 5x0.1mL | 1841 EUR |
Dkk-1 Polyclonal Antibody |
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| MBS9409972-005mL | MyBiosource | 0.05mL | 245 EUR |
Dkk-1 Polyclonal Antibody |
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| MBS9409972-01mL | MyBiosource | 0.1mL | 305 EUR |
Dkk-1 Polyclonal Antibody |
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| MBS9409972-5x01mL | MyBiosource | 5x0.1mL | 1230 EUR |
Dkk-1 Polyclonal Antibody |
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| MBS8526543-01mg | MyBiosource | 0.1mg | 305 EUR |
Dkk-1 Polyclonal Antibody |
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| MBS8526543-01mLAF405L | MyBiosource | 0.1mL(AF405L) | 465 EUR |
Dkk-1 Polyclonal Antibody |
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| MBS8526543-01mLAF405S | MyBiosource | 0.1mL(AF405S) | 465 EUR |
Dkk-1 Polyclonal Antibody |
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| MBS8526543-01mLAF610 | MyBiosource | 0.1mL(AF610) | 465 EUR |
Dkk-1 Polyclonal Antibody |
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| MBS8526543-01mLAF635 | MyBiosource | 0.1mL(AF635) | 465 EUR |
Dkk-1 Polyclonal Antibody |
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| MBS2534622-002mL | MyBiosource | 0.02mL | 140 EUR |
Dkk-1 Polyclonal Antibody |
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| MBS2534622-006mL | MyBiosource | 0.06mL | 180 EUR |
Dkk-1 Polyclonal Antibody |
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| MBS2534622-012mL | MyBiosource | 0.12mL | 260 EUR |
Dkk-1 Polyclonal Antibody |
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| MBS2534622-02mL | MyBiosource | 0.2mL | 405 EUR |
Dkk-1 Monoclonal Antibody |
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| UB-GEN-3319 | UpingBio | 100 ul | 200 EUR |
Dkk-1 Polyclonal Antibody |
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| UB-GEN-4258 | UpingBio | 100 ul | 200 EUR |
DKK-1 Neutralizing Antibody |
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| MBS8101470-02mg | MyBiosource | 0.2mg | 280 EUR |
DKK-1 Neutralizing Antibody |
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| MBS8101470-05mg | MyBiosource | 0.5mg | 375 EUR |
DKK-1 Neutralizing Antibody |
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| MBS8101470-5x05mg | MyBiosource | 5x0.5mg | 1545 EUR |
Dkk-2 |
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| GT15222 | Neuromics | 100 ug | 631.2 EUR |
DKK 1 Recombinant Protein |
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| 96-236 | ProSci | 0.1 mg | 752.1 EUR |
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Description: Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK1 takes part in embryonic development through its inhibition of the WNT signaling pathway, binds to LRP6 with high affinity and prevents the Frizzled-Wnt-LRP6 complex formation in response to Wnts. DKK1 promotes LRP6 internalization and degradation when it forms a ternary complex with the cell surface receptor Kremen.DKK1 not olny functions as a head inducer during development, but also regulates joint remodeling and bone formation, which suggests roles for DKK1 in the pathogenesis of rheumatoid arthritis and multiple myeloma. More recently research reported, DKK1 impacts eye development from a defined developmental time point on, and is critical for lens separation from the surface ectoderm via β-catenin mediated Pdgfrα and E-cadherin expression. |
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DKK 1 Recombinant Protein |
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| 96-237 | ProSci | 0.025 mg | 619.8 EUR |
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Description: Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK1 takes part in embryonic development through its inhibition of the WNT signaling pathway, binds to LRP6 with high affinity and prevents the Frizzled-Wnt-LRP6 complex formation in response to Wnts. DKK1 promotes LRP6 internalization and degradation when it forms a ternary complex with the cell surface receptor Kremen.DKK1 not olny functions as a head inducer during development, but also regulates joint remodeling and bone formation, which suggests roles for DKK1 in the pathogenesis of rheumatoid arthritis and multiple myeloma. More recently research reported, DKK1 impacts eye development from a defined developmental time point on, and is critical for lens separation from the surface ectoderm via β-catenin mediated Pdgfrα and E-cadherin expression. |
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Rat DKK-1 ELISA Kit |
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| EK5668 | SAB | 96 tests | 599 EUR |
Dkk-1 (Human) ELISA Kit |
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| EKA52037-5x96T | Biomatik Corporation | 5x96T | Ask for price |
Dkk-1 (Human) ELISA Kit |
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| EKA52037-96T | Biomatik Corporation | 96T | 446.9 EUR |
Human Dkk-1 ELISA KIT |
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| E42EH-269 | EnoGene | 96T/48T | Ask for price |
Mouse Dkk-1 ELISA KIT |
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| E42EM-173 | EnoGene | 96T/48T | Ask for price |
Human Dkk-1 ELISA Kit |
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| E28L0566 | EnoGene | 96T | 666.67 EUR |
Mouse Dkk-1 ELISA Kit |
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| E28L0661 | EnoGene | 96T | 666.67 EUR |
Human DKK-1 ELISA Kit |
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| EK5390 | SAB | 96 tests | 599 EUR |
Human DKK-1 ELISA KIT |
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| EF000090 | Nova Lifetech | 96tests | 566 EUR |
Human Dkk-1 ELISA Kit |
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| GWB-SKR221 | GenWay Biotech | 96 Tests | Ask for price |
Human DKK-1 ELISA kit |
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| LF-EK50797 | Abfrontier | 1×96T | 777.6 EUR |
Recombinant Human DKK-2/DKK2 Protein, Fc Tag & His Tag. |
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| E40KMH987 | EnoGene | 20ug | 495 EUR |
Anti-Human Dkk-1 Antibody |
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| 101-M380 | ReliaTech | 100 µg | 399 EUR |
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Description: Dkk1 is a Dickkopf-related protein that inhibits Wnt signaling by binding the Wnt coreceptor LRP5/6. It also binds Kremen1 and Kremen2. Dkk1 is important in embryonic development. |
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Anti-Human Dkk-1 Antibody |
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| 101-M426 | ReliaTech | 100 µg | 399 EUR |
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Description: Dkk1 is a Dickkopf-related protein that inhibits Wnt signaling by binding the Wnt coreceptor LRP5/6. It also binds Kremen1 and Kremen2. Dkk1 is important in embryonic development. |
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Anti-Human Dkk-1 Antibody |
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| 102-PA33 | ReliaTech | 200 µg | 204.75 EUR |
|
Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 fused to a C terminal His-tag derived from E. coli is a 26 kDa protein containing 235 amino-acid residues. |
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Anti-Human Dkk-1 Antibody |
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| 102-PA33S | ReliaTech | 100 µg | 126 EUR |
|
Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 fused to a C terminal His-tag derived from E. coli is a 26 kDa protein containing 235 amino-acid residues. |
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DKK-1 (CHO-expressed), Mouse |
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| HY-P7154 | MedChemExpress | 50ug | 914.4 EUR |
DKK-1 (HEK293-expressed), Human |
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| HY-P7155A | MedChemExpress | 50ug | 1011.6 EUR |
human Dkk-1 Recombinant Protein |
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| 100-407 | ReliaTech | 10 µg | 196.35 EUR |
|
Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 expressed in human 293 cells is a 35-40 kDa glycoprotein containing 235 amino-acid residues. |
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human Dkk-1 Recombinant Protein |
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| 100-407S | ReliaTech | 2 µg | 92.4 EUR |
|
Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 expressed in human 293 cells is a 35-40 kDa glycoprotein containing 235 amino-acid residues. |
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Human Dkk-1 Recombinant Protein |
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| 200-013 | ReliaTech | 20 µg | 136.5 EUR |
|
Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 fused to a C terminal His-tag derived from E. coli is a 26 kDa protein containing 235 amino-acid residues. |
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Human Dkk-1 Recombinant Protein |
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| 200-013S | ReliaTech | 5 µg | 92.4 EUR |
|
Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 fused to a C terminal His-tag derived from E. coli is a 26 kDa protein containing 235 amino-acid residues. |
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Recombinant Human DKK-1 Protein |
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| PROTO94907-3 | BosterBio | 10ug | 380.4 EUR |
|
Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 expressed in human 293 cells is a 35-40 kDa glycoprotein containing 235 amino-acid residues. |
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Recombinant Mouse Dkk-1 Protein |
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| MBS9141892-0005mg | MyBiosource | 0.005mg | 165 EUR |
Recombinant Mouse Dkk-1 Protein |
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| MBS9141892-002mg | MyBiosource | 0.02mg | 235 EUR |
Recombinant Mouse Dkk-1 Protein |
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| MBS9141892-005mg | MyBiosource | 0.05mg | 435 EUR |
Recombinant Mouse Dkk-1 Protein |
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| MBS9141892-01mg | MyBiosource | 0.1mg | 650 EUR |
Recombinant Mouse Dkk-1 Protein |
|||
| MBS9141892-5x01mg | MyBiosource | 5x0.1mg | 2750 EUR |
Recombinant mouse Dkk-1 protein |
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| MBS201385-001mg | MyBiosource | 0.01mg | 240 EUR |
Recombinant mouse Dkk-1 protein |
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| MBS201385-002mg | MyBiosource | 0.02mg | 320 EUR |
Recombinant mouse Dkk-1 protein |
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| MBS201385-005mg | MyBiosource | 0.05mg | 375 EUR |
Recombinant mouse Dkk-1 protein |
|||
| MBS201385-01mg | MyBiosource | 0.1mg | 550 EUR |
Recombinant mouse Dkk-1 protein |
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| MBS201385-025mg | MyBiosource | 0.25mg | 885 EUR |
Dkk-1 Rabbit Polyclonal Antibody |
|||
| ES4292-100ul | ELK Biotech | 100ul | 124 EUR |
|
Description: A Rabbit Polyclonal antibody against Dkk-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
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Dkk-1 Rabbit Polyclonal Antibody |
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| ES4292-50ul | ELK Biotech | 50ul | 74 EUR |
|
Description: A Rabbit Polyclonal antibody against Dkk-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
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Dkk-1 Polyclonal Conjugated Antibody |
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| C41928 | SAB | 100ul | 476.4 EUR |
Dkk-1 Polyclonal Conjugated Antibody |
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| MBS9450395-01mLAF350 | MyBiosource | 0.1mL(AF350) | 480 EUR |
Dkk-1 Polyclonal Conjugated Antibody |
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| MBS9450395-01mLAF405 | MyBiosource | 0.1mL(AF405) | 480 EUR |
Dkk-1 Polyclonal Conjugated Antibody |
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| MBS9450395-01mLAF488 | MyBiosource | 0.1mL(AF488) | 480 EUR |
Dkk-1 Polyclonal Conjugated Antibody |
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| MBS9450395-01mLAF555 | MyBiosource | 0.1mL(AF555) | 480 EUR |
Dkk-1 Polyclonal Conjugated Antibody |
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| MBS9450395-01mLBiotin | MyBiosource | 0.1mL(Biotin) | 480 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (AP) |
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| MBS6414187-01mL | MyBiosource | 0.1mL | 950 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (AP) |
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| MBS6414187-5x01mL | MyBiosource | 5x0.1mL | 4120 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (PE) |
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| MBS6414197-01mL | MyBiosource | 0.1mL | 950 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (PE) |
|||
| MBS6414197-5x01mL | MyBiosource | 5x0.1mL | 4120 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (AP) |
|||
| MBS6414198-01mL | MyBiosource | 0.1mL | 950 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (AP) |
|||
| MBS6414198-5x01mL | MyBiosource | 5x0.1mL | 4120 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (PE) |
|||
| MBS6414208-01mL | MyBiosource | 0.1mL | 950 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (PE) |
|||
| MBS6414208-5x01mL | MyBiosource | 5x0.1mL | 4120 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (APC) |
|||
| MBS6414188-01mL | MyBiosource | 0.1mL | 950 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (APC) |
|||
| MBS6414188-5x01mL | MyBiosource | 5x0.1mL | 4120 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (HRP) |
|||
| MBS6414191-01mL | MyBiosource | 0.1mL | 950 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (HRP) |
|||
| MBS6414191-5x01mL | MyBiosource | 5x0.1mL | 4120 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (APC) |
|||
| MBS6414199-01mL | MyBiosource | 0.1mL | 950 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (APC) |
|||
| MBS6414199-5x01mL | MyBiosource | 5x0.1mL | 4120 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (HRP) |
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| MBS6414202-01mL | MyBiosource | 0.1mL | 950 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (HRP) |
|||
| MBS6414202-5x01mL | MyBiosource | 5x0.1mL | 4120 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (FITC) |
|||
| MBS6414190-01mL | MyBiosource | 0.1mL | 950 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (FITC) |
|||
| MBS6414190-5x01mL | MyBiosource | 5x0.1mL | 4120 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (FITC) |
|||
| MBS6414201-01mL | MyBiosource | 0.1mL | 950 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (FITC) |
|||
| MBS6414201-5x01mL | MyBiosource | 5x0.1mL | 4120 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (Biotin) |
|||
| MBS6414189-01mL | MyBiosource | 0.1mL | 950 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (Biotin) |
|||
| MBS6414189-5x01mL | MyBiosource | 5x0.1mL | 4120 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (Biotin) |
|||
| MBS6414200-01mL | MyBiosource | 0.1mL | 950 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (Biotin) |
|||
| MBS6414200-5x01mL | MyBiosource | 5x0.1mL | 4120 EUR |
Human Dkk-3 |
|||
| MBS691794-0002mg | MyBiosource | 0.002mg | 300 EUR |
Human Dkk-3 |
|||
| MBS691794-001mg | MyBiosource | 0.01mg | 450 EUR |
Human Dkk-3 |
|||
| MBS691794-5x001mg | MyBiosource | 5x0.01mg | 1725 EUR |
Human Dkk-2 |
|||
| MBS692245-0002mg | MyBiosource | 0.002mg | 300 EUR |
Human Dkk-2 |
|||
| MBS692245-001mg | MyBiosource | 0.01mg | 450 EUR |
Human Dkk-2 |
|||
| MBS692245-5x001mg | MyBiosource | 5x0.01mg | 1725 EUR |
Human Dkk-2 |
|||
| MBS692272-0005mg | MyBiosource | 0.005mg | 250 EUR |
Human Dkk-2 |
|||
| MBS692272-002mg | MyBiosource | 0.02mg | 360 EUR |
Human Dkk-2 |
|||
| MBS692272-5x002mg | MyBiosource | 5x0.02mg | 1325 EUR |
Dkk-3 antibody |
|||
| 22898 | SAB | 100ul | 479 EUR |
Dkk-3 antibody |
|||
| 22898-100ul | SAB | 100ul | 468 EUR |
Dkk-3 antibody |
|||
| MBS9406033-01mL | MyBiosource | 0.1mL | 420 EUR |
Dkk-3 antibody |
|||
| MBS9406033-5x01mL | MyBiosource | 5x0.1mL | 1740 EUR |
Dkk-3 Antibody |
|||
| C15354-100ul | Assay Biotech | 100μl | 217 EUR |
|
Description: Dkk-3 Rabbit Polyclonal Antibody |
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Dkk-3 Antibody |
|||
| C15354-50ul | Assay Biotech | 50μl | 143.5 EUR |
|
Description: Dkk-3 Rabbit Polyclonal Antibody |
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Mouse Dkk-1 Protein, His Tag |
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| DK1-M52H6 | ACROBIOSYSTEMS | 500ug | 374.5 EUR |
|
Description: Mouse Dkk-1, His Tag (DK1-M52H6) is expressed from human 293 cells (HEK293). It contains AA Thr 32 - His 272 (Accession # O54908). |
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Dkk-1 (Human) LumiAb ELISA Kit |
|||
| MBS9510975-10x96StripWells | MyBiosource | 10x96-Strip-Wells | 4355 EUR |
Dkk-1 (Human) LumiAb ELISA Kit |
|||
| MBS9510975-5x96StripWells | MyBiosource | 5x96-Strip-Wells | 2225 EUR |
Dkk-1 (Human) LumiAb ELISA Kit |
|||
| MBS9510975-96StripWells | MyBiosource | 96-Strip-Wells | 500 EUR |
Human DKK-1 PicoKine ELISA Kit |
|||
| EK0867 | BosterBio | 96 wells | 510 EUR |
|
Description: For quantitative detection of human DKK1 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
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Human DKK-1 PicoKine ELISA Kit |
|||
| MBS176546-5x96StripWells | MyBiosource | 5x96-Strip-Wells | 2755 EUR |
Human DKK-1 PicoKine ELISA Kit |
|||
| MBS176546-96StripWells | MyBiosource | 96-Strip-Wells | 600 EUR |
Dkk-1 (Human) Sandwich ELISA Kit |
|||
| OK-0326 | Assay Biotech | 1Kit | 280 EUR |
|
Description: Dkk-1 (Human) Colorimetric Sandwich ELISA Kit |
|||
Dkk-1 (Human) OmniKine ELISA Kit |
|||
| MBS9502047-1x96Wells | MyBiosource | 1x96Wells | 500 EUR |
Dkk-1 (Human) OmniKine ELISA Kit |
|||
| MBS9502047-5x96Wells | MyBiosource | 5x96Wells | 2300 EUR |
Dkk-1 (mouse), (recombinant) (His-tag) |
|||
| MBS565898-02mg | MyBiosource | 0.2mg | 1210 EUR |
Dkk-1 (mouse), (recombinant) (His-tag) |
|||
| MBS565898-5x02mg | MyBiosource | 5x0.2mg | 5405 EUR |
Mouse Monoclonal anti-human Dkk-1 |
|||
| hAP-0246 | Angio Proteomie | 100ug | 250 EUR |
Mouse Monoclonal anti-human Dkk-1 |
|||
| hAP-0246A | Angio Proteomie | 100ug | 250 EUR |
Sheep Polyclonal anti-Human Dkk-1 |
|||
| hAP-5846 | Angio Proteomie | 50ug | 400 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (MaxLight 405) |
|||
| MBS6414192-01mL | MyBiosource | 0.1mL | 950 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (MaxLight 405) |
|||
| MBS6414192-5x01mL | MyBiosource | 5x0.1mL | 4120 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (MaxLight 490) |
|||
| MBS6414193-01mL | MyBiosource | 0.1mL | 950 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (MaxLight 490) |
|||
| MBS6414193-5x01mL | MyBiosource | 5x0.1mL | 4120 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (MaxLight 550) |
|||
| MBS6414194-01mL | MyBiosource | 0.1mL | 950 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (MaxLight 550) |
|||
| MBS6414194-5x01mL | MyBiosource | 5x0.1mL | 4120 EUR |
DKK1 (Dickkopf-1, DKK-1, SK) (MaxLight 650) |
|||
| MBS6414195-01mL | MyBiosource | 0.1mL | 950 EUR |
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