The electrocardiogram (ECG) is a generally used scientific software that displays cardiac excitability and illness. Many parameters are will be measured and with the development of methodology can now be quantified in an automatic trend, with accuracy and at scale.
Furthermore, these measurements will be heritable and thus genome vast affiliation research inform the underpinning organic mechanisms. In this assessment we describe how we’ve used the sources in UK Biobank to undertake such work. In specific, we deal with a substudy uniquely describing the response to train carried out at scale with accompanying genetic info.
A Body Shape Index (ABSI), hip index, and risk of most cancers in the UK Biobank cohort
Abdominal dimension is related positively with the risk of some cancers however the affect of physique mass index (BMI) and gluteofemoral dimension is unclear as a result of waist and hip circumference are strongly correlated with BMI. We examined associations of 33 cancers with A Body Shape Index (ABSI) and hip index (HI), that are impartial of BMI by design, and in contrast these with waist and hip circumference, utilizing multivariable Cox proportional hazards fashions in UK Biobank.
During a imply follow-up of seven years, 14,682 incident cancers had been ascertained in 200,289 males and 12,965 cancers in 230,326 ladies. In males, ABSI was related positively with cancers of the top and neck (hazard ratio HR = 1.14; 95% confidence interval 1.03-1.26 per one customary deviation increment), esophagus (adenocarcinoma, HR = 1.27; 1.12-1.44), gastric cardia (HR = 1.31; 1.07-1.61), colon (HR = 1.18; 1.10-1.26), rectum (HR = 1.13; 1.04-1.22), lung (adenocarcinoma, HR = 1.16; 1.03-1.30; squamous cell carcinoma [SCC], HR = 1.33; 1.17-1.52), and bladder (HR = 1.15; 1.04-1.27), whereas HI was related inversely with cancers of the esophagus (adenocarcinoma, HR = 0.89; 0.79-1.00), gastric cardia (HR = 0.79; 0.65-0.96), colon (HR = 0.92; 0.86-0.98), liver (HR = 0.86; 0.75-0.98), and a number of myeloma (HR = 0.86; 0.75-1.00).
In ladies, ABSI was related positively with cancers of the top and neck (HR = 1.27; 1.10-1.48), esophagus (SCC, HR = 1.37; 1.07-1.76), colon (HR = 1.08; 1.01-1.16), lung (adenocarcinoma, HR = 1.17; 1.06-1.29; SCC, HR = 1.40; 1.20-1.63; small cell, HR = 1.39; 1.14-1.69), kidney (clear-cell, HR = 1.25; 1.03-1.50), and post-menopausal endometrium (HR = 1.11; 1.02-1.20), whereas HI was related inversely with pores and skin SCC (HR = 0.91; 0.83-0.99), post-menopausal kidney most cancers (HR = 0.77; 0.67-0.88), and post-menopausal melanoma (HR = 0.90; 0.83-0.98).
Unusually, ABSI was related inversely with melanoma in males (HR = 0.89; 0.82-0.96) and pre-menopausal ladies (HR = 0.77; 0.65-0.91). Waist and hip circumference mirrored associations with BMI, when examined individually, and supplied biased risk estimates, when mixed with BMI. In conclusion, preferential optimistic associations of ABSI or inverse of HI with a number of main cancers point out an necessary function of things figuring out physique form in most cancers improvement.
Brain imaging earlier than and after COVID-19 in UK Biobank
There is powerful proof for brain-related pathologies in COVID-19, a few of which may very well be a consequence of viral neurotropism. The overwhelming majority of mind imaging research up to now have targeted on qualitative, gross pathology of reasonable to extreme circumstances, typically carried out on hospitalised sufferers. It stays unknown nevertheless whether or not the influence of COVID-19 will be detected in milder circumstances, in a quantitative and automated method, and whether or not this could reveal a doable mechanism for the unfold of the illness.
UK Biobank scanned over 40,000 individuals earlier than the beginning of the COVID-19 pandemic, making it doable to ask again in 2021 tons of of previously-imaged individuals for a second imaging go to. Here, we studied the results of the illness in the mind utilizing multimodal knowledge from 782 individuals from the UK Biobank COVID-19 re-imaging research, with 394 individuals having examined optimistic for SARS-CoV-2 an infection between their two scans. We used structural and practical mind scans from earlier than and after an infection, to match longitudinal mind adjustments between these 394 COVID-19 sufferers and 388 controls who had been matched for age, intercourse, ethnicity and interval between scans.
We recognized important results of COVID-19 in the mind with a lack of gray matter in the left parahippocampal gyrus, the left lateral orbitofrontal cortex and the left insula. When trying over your entire cortical floor, these outcomes prolonged to the anterior cingulate cortex, supramarginal gyrus and temporal pole. We additional in contrast COVID-19 sufferers who had been hospitalised (n=15) with those that had not (n=379), and whereas outcomes weren’t important, we discovered comparatively related findings to the COVID-19 vs management group comparability, with, in addition, a better lack of gray matter in the cingulate cortex, central nucleus of the amygdala and hippocampal cornu ammonis (all |Z|>3). Our findings thus constantly relate to lack of gray matter in limbic cortical areas immediately linked to the first olfactory and gustatory system.
Unlike in submit hoc illness research, the provision of pre-infection imaging knowledge helps keep away from the hazard of pre-existing risk components or scientific situations being mis-interpreted as illness results. Since a doable entry level of the virus to the central nervous system is likely to be through the olfactory mucosa and the olfactory bulb, these mind imaging outcomes is likely to be the in vivo hallmark of the unfold of the illness (or the virus itself) through olfactory and gustatory pathways.
BBMRI-ERIC Negotiator: Implementing Efficient Access to Biobanks
Various organic sources, similar to biobanks and disease-specific registries, have develop into indispensable sources to raised perceive the epidemiology and organic mechanisms of illness and are basic for advancing medical analysis. Nevertheless, biobanks and related sources nonetheless face important challenges to develop into extra findable and accessible by customers on each nationwide and world scales.
One of the primary challenges for customers is to seek out related sources utilizing cataloging and search providers such because the BBMRI-ERIC Directory, operated by European Research Infrastructure on Biobanking and Biomolecular Resources (BBMRI-ERIC), as these typically don’t include the knowledge wanted by the researchers to resolve if the useful resource has related materials/knowledge; these sources are solely weakly characterised. Hence, the researcher is usually left with too many sources to discover and examine. In addition, sources typically have advanced procedures for accessing holdings, notably for depletable organic supplies.
This article focuses on designing a system for efficient negotiation of entry to holdings, in which a researcher can strategy many sources concurrently, whereas giving every useful resource workforce the flexibility to implement their very own mechanisms to test if the fabric/knowledge can be found and to resolve if entry needs to be supplied. The BBMRI-ERIC has developed and carried out an entry and negotiation software known as the BBMRI-ERIC Negotiator.
Activin-A |
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| ant-029 | ProSpec Tany | 5µg | 60 EUR |
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Description: Polyclonal Rabbit Anti Human Activin-A |
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Activin-A Activin A Human Recombinant Protein, Plant |
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| PROTP08476 | BosterBio | Regular: 10ug | 380.4 EUR |
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Description: Activin A human Recombinant produced in Nicotiana benthamiana plant is a disulfide-linked homodimers of two betaA chains, each containing 116 amino residues (molecular formula C600H911N173O174S13) and 6-His-tag at the N-terminal having the total molecular mass of 27.4kDa. |
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Activin A ELISA Kit| Sheep Activin A ELISA Kit |
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| EF019524 | Nova Lifetech | 96tests | 566 EUR |
Activin A, Active |
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| cyt-145 | ProSpec Tany | 2µg | 60 EUR |
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Description: Recombinant Human Activin-A, Active |
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Activin A, CF |
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| PR15010CF | Neuromics | 50 ug | 1250.4 EUR |
rHu Activin A |
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| AK8534-0002 | Akron Biotech | 2µg | Ask for price |
rHu Activin A |
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| AK8534-0010 | Akron Biotech | 10µg | Ask for price |
rHu Activin A |
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| AK8534-0100 | Akron Biotech | 100µg | Ask for price |
rHu Activin A |
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| AK8534-1000 | Akron Biotech | 1mg | Ask for price |
Activin A, Plant |
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| cyt-052 | ProSpec Tany | 2µg | 60 EUR |
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Description: Recombinant Human Activin-A, Plant |
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Human Activin-A |
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| MBS691471-0002mg | MyBiosource | 0.002mg | 300 EUR |
Human Activin-A |
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| MBS691471-001mg | MyBiosource | 0.01mg | 450 EUR |
Human Activin-A |
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| MBS691471-5x001mg | MyBiosource | 5x0.01mg | 1725 EUR |
Human Activin-A |
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| MBS692288-0002mg | MyBiosource | 0.002mg | 300 EUR |
Human Activin-A |
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| MBS692288-001mg | MyBiosource | 0.01mg | 450 EUR |
Human Activin-A |
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| MBS692288-5x001mg | MyBiosource | 5x0.01mg | 1725 EUR |
Activin A protein |
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| 30R-AA005 | Fitzgerald | 10 ug | 312 EUR |
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Description: Purified recombinant Human Activin A protein |
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Activin A protein |
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| 30R-AA036 | Fitzgerald | 10 ug | 312 EUR |
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Description: Purified recombinant Human Activin A protein |
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Activin A protein |
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| MBS538290-001mg | MyBiosource | 0.01mg | 465 EUR |
Activin A protein |
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| MBS538290-5x001mg | MyBiosource | 5x0.01mg | 1945 EUR |
Activin A protein |
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| MBS539355-001mg | MyBiosource | 0.01mg | 465 EUR |
Activin A protein |
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| MBS539355-5x001mg | MyBiosource | 5x0.01mg | 1945 EUR |
Activin-A Protein |
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| 20-abx262096 | Abbexa |
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Activin-A Protein |
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| 20-abx262946 | Abbexa |
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Activin-A Protein |
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| 20-abx262947 | Abbexa |
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Activin-A Protein |
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| abx262096-10mg | Abbexa | 10 mg | 3550 EUR |
Activin-A Protein |
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| abx262096-5mg | Abbexa | 5 mg | 325 EUR |
Activin-A Protein |
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| abx262946-10mg | Abbexa | 10 mg | 325 EUR |
Activin-A Protein |
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| abx262946-25mg | Abbexa | 25 mg | 5462.5 EUR |
Activin-A Protein |
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| abx262946-5mg | Abbexa | 5 mg | 225 EUR |
Activin-A Antibody |
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| 20-abx137208 | Abbexa |
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Activin A Precursor |
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| MBS606801-05mg | MyBiosource | 0.5mg | 1105 EUR |
Activin A Precursor |
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| MBS606801-5x05mg | MyBiosource | 5x0.5mg | 4830 EUR |
Active Activin A (ACVA) |
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| APA001Hu01 | Cloud-Clone | 10ug | 264 EUR |
Active Activin A (ACVA) |
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| 4-APA001Hu01 | Cloud-Clone |
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Description: Recombinant Human Activin A expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells |
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Active Activin A (ACVA) |
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| RPU55431-100ug | Biomatik Corporation | 100ug | 812.9 EUR |
Active Activin A (ACVA) |
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| RPU55431-1mg | Biomatik Corporation | 1mg | 3603.6 EUR |
Active Activin A (ACVA) |
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| RPU55431-50ug | Biomatik Corporation | 50ug | 653.4 EUR |
Active Activin A (ACVA) |
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| MBS2105043-001mg | MyBiosource | 0.01mg | 220 EUR |
Active Activin A (ACVA) |
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| MBS2105043-005mg | MyBiosource | 0.05mg | 435 EUR |
Active Activin A (ACVA) |
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| MBS2105043-01mg | MyBiosource | 0.1mg | 660 EUR |
Active Activin A (ACVA) |
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| MBS2105043-02mg | MyBiosource | 0.2mg | 815 EUR |
Active Activin A (ACVA) |
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| MBS2105043-05mg | MyBiosource | 0.5mg | 1575 EUR |
Activin A GMP, CF |
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| PR15122CF | Neuromics | 50 ug | 1984.8 EUR |
Activin-A, Active Protein |
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| 20-abx262945 | Abbexa |
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Activin-A Active Protein |
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| 20-abx260392 | Abbexa |
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Activin-A, Active Protein |
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| abx262945-10mg | Abbexa | 10 mg | 325 EUR |
Activin-A, Active Protein |
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| abx262945-25mg | Abbexa | 25 mg | 5462.5 EUR |
Activin-A, Active Protein |
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| abx262945-5mg | Abbexa | 5 mg | 225 EUR |
Activin-A Active Protein |
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| abx260392-10g | Abbexa | 10 µg | 325 EUR |
Activin-A Active Protein |
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| abx260392-1mg | Abbexa | 1 mg | 1975 EUR |
Activin-A Active Protein |
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| abx260392-2g | Abbexa | 2 µg | 225 EUR |
Activin A ELISA Kit |
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| MBS495318-5x96Tests | MyBiosource | 5x96Tests | 3510 EUR |
Activin A ELISA Kit |
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| MBS495318-96Tests | MyBiosource | 96Tests | 760 EUR |
Rat Activin-A Protein |
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| abx262947-10mg | Abbexa | 10 mg | 325 EUR |
Rat Activin-A Protein |
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| abx262947-25mg | Abbexa | 25 mg | 5462.5 EUR |
Rat Activin-A Protein |
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| abx262947-5mg | Abbexa | 5 mg | 225 EUR |
Activin A (ACVA) Antibody |
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| 20-abx129133 | Abbexa |
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Activin A (ACVA) Antibody |
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| abx129133-100l | Abbexa | 100 µl | 212.5 EUR |
Activin A (ACVA) Antibody |
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| abx129133-1ml | Abbexa | 1 ml | 475 EUR |
Activin A (ACVA) Antibody |
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| abx129133-200l | Abbexa | 200 µl | 250 EUR |
Activin A (ACVA) Antibody |
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| abx137208-01mg | Abbexa | 0.1 mg | 225 EUR |
Activin-A, Plant Protein |
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| 20-abx262335 | Abbexa |
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Activin A, Plant-Active |
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| cyt-414 | ProSpec Tany | 1µg | 60 EUR |
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Description: Recombinant Human Activin-A Active |
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Activin-A, Plant Protein |
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| abx262335-10mg | Abbexa | 10 mg | 325 EUR |
Activin-A, Plant Protein |
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| abx262335-25mg | Abbexa | 25 mg | 6500 EUR |
Activin-A, Plant Protein |
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| abx262335-5mg | Abbexa | 5 mg | 225 EUR |
Activin A, rat recombinant |
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| 4726-10 | Biovision | each | 411.6 EUR |
Activin A, rat recombinant |
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| 4726-100 | Biovision | each | 1546.8 EUR |
Activin A, rat recombinant |
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| 4726-1000 | Biovision | each | 10538.4 EUR |
Recombinant Rat Activin A |
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| MBS7609531-005mg | MyBiosource | 0.05mg | 345 EUR |
Recombinant Rat Activin A |
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| MBS7609531-02mg | MyBiosource | 0.2mg | 635 EUR |
Recombinant Rat Activin A |
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| MBS7609531-1mg | MyBiosource | 1mg | 1800 EUR |
Recombinant Rat Activin A |
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| MBS7609531-5x1mg | MyBiosource | 5x1mg | 6955 EUR |
Recombinant Activin A (ACVA) |
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| RPA001Hu01 | Cloud-Clone | 10ug | 176 EUR |
Recombinant Activin A (ACVA) |
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| 4-RPA001Hu01 | Cloud-Clone |
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Description: Recombinant Human Activin A expressed in: E.coli |
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Recombinant Activin A (ACVA) |
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| RPU52965-100ug | Biomatik Corporation | 100ug | 542.3 EUR |
Recombinant Activin A (ACVA) |
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| RPU52965-1mg | Biomatik Corporation | 1mg | 2402.4 EUR |
Recombinant Activin A (ACVA) |
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| RPU52965-50ug | Biomatik Corporation | 50ug | 435.6 EUR |
Activin-A Rat Recombinant |
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| rAP-2129 | Angio Proteomie | Inquiry | Ask for price |
Recombinant Rat Activin-A |
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| cyt-147-10g | ProSpec Tany | 10µg | 145 EUR |
Recombinant Rat Activin-A |
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| cyt-147-1mg | ProSpec Tany | 1mg | 3500 EUR |
Recombinant Rat Activin-A |
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| cyt-147-2g | ProSpec Tany | 2µg | 60 EUR |
Recombinant Rat Activin-A |
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| MBS144774-0002mg | MyBiosource | 0.002mg | 240 EUR |
Recombinant Rat Activin-A |
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| MBS144774-001mg | MyBiosource | 0.01mg | 310 EUR |
Recombinant Rat Activin-A |
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| MBS144774-1mg | MyBiosource | 1mg | 4460 EUR |
Recombinant Rat Activin-A |
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| MBS144774-5x1mg | MyBiosource | 5x1mg | 19750 EUR |
Recombinant Activin A (ACVA) |
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| MBS2028864-001mg | MyBiosource | 0.01mg | 170 EUR |
Recombinant Activin A (ACVA) |
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| MBS2028864-005mg | MyBiosource | 0.05mg | 305 EUR |
Recombinant Activin A (ACVA) |
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| MBS2028864-01mg | MyBiosource | 0.1mg | 460 EUR |
Recombinant Activin A (ACVA) |
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| MBS2028864-02mg | MyBiosource | 0.2mg | 560 EUR |
Recombinant Activin A (ACVA) |
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| MBS2028864-05mg | MyBiosource | 0.5mg | 1065 EUR |
Activin A, human recombinant |
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| 4724-10 | Biovision | each | 411.6 EUR |
Activin A, human recombinant |
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| 4724-100 | Biovision | each | 1546.8 EUR |
Activin A, human recombinant |
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| 4724-1000 | Biovision | each | 10538.4 EUR |
Activin A, mouse recombinant |
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| 4725-10 | Biovision | each | 411.6 EUR |
Activin A, mouse recombinant |
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| 4725-100 | Biovision | each | 1546.8 EUR |
Activin A, mouse recombinant |
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| 4725-1000 | Biovision | each | 10538.4 EUR |
Activin A, recombinant (Human) |
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| 080-05A | PHOENIX PEPTIDE | 5 μg | 238.68 EUR |
Activin A Human Recombinant |
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| rAP-2131 | Angio Proteomie | Inquiry | Ask for price |
Activin A, Human Recombinant |
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| rAP-6005 | Angio Proteomie | Inquiry | Ask for price |
Recombinant Mouse Activin A |
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| MBS7610337-005mg | MyBiosource | 0.05mg | 345 EUR |
Recombinant Mouse Activin A |
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| MBS7610337-02mg | MyBiosource | 0.2mg | 635 EUR |
Recombinant Mouse Activin A |
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| MBS7610337-1mg | MyBiosource | 1mg | 1800 EUR |
Recombinant Mouse Activin A |
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| MBS7610337-5x1mg | MyBiosource | 5x1mg | 6955 EUR |
Recombinant Human Activin-A |
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| 7-00001 | Cusabio | 2µg | Ask for price |
Recombinant Human Activin-A |
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| 7-00002 | CHI Scientific | 10µg | Ask for price |
Recombinant Human Activin-A |
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| 7-00003 | CHI Scientific | 1mg | Ask for price |
Activin-A Mouse Recombinant |
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| rAP-2128 | Angio Proteomie | Inquiry | Ask for price |
Recombinant Mouse Activin-A |
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| cyt-146-10g | ProSpec Tany | 10µg | 145 EUR |
Recombinant Mouse Activin-A |
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| cyt-146-1mg | ProSpec Tany | 1mg | 3500 EUR |
Recombinant Mouse Activin-A |
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| cyt-146-2g | ProSpec Tany | 2µg | 60 EUR |
Recombinant Human Activin-A |
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| cyt-569-10g | ProSpec Tany | 10µg | 145 EUR |
Recombinant Human Activin-A |
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| cyt-569-1mg | ProSpec Tany | 1mg | 2700 EUR |
Recombinant Human Activin-A |
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| cyt-569-2g | ProSpec Tany | 2µg | 60 EUR |
Recombinant Human Activin-A |
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| MBS143284-0002mg | MyBiosource | 0.002mg | 240 EUR |
Recombinant Human Activin-A |
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| MBS143284-001mg | MyBiosource | 0.01mg | 310 EUR |
Recombinant Human Activin-A |
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| MBS143284-1mg | MyBiosource | 1mg | 2880 EUR |
Recombinant Human Activin-A |
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| MBS143284-5x1mg | MyBiosource | 5x1mg | 12630 EUR |
Recombinant Mouse Activin-A |
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| MBS145173-0002mg | MyBiosource | 0.002mg | 240 EUR |
Recombinant Mouse Activin-A |
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| MBS145173-001mg | MyBiosource | 0.01mg | 310 EUR |
Recombinant Mouse Activin-A |
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| MBS145173-1mg | MyBiosource | 1mg | 4460 EUR |
Recombinant Mouse Activin-A |
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| MBS145173-5x1mg | MyBiosource | 5x1mg | 19750 EUR |
Activin A Recombinant Protein |
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| 91-572 | ProSci | 0.05 mg | 821.4 EUR |
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Description: Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Activins are homodimers or heterodimers of the various beta subunit isoforms, while inhibins are heterodimers of a unique alpha subunit and one of the various beta subunits. |
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Activin A Recombinant Protein |
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| 96-784 | ProSci | 0.025 mg | 588.3 EUR |
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Description: Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activin enhances FSH biosynthesis and secretion, and participates in the regulation of the menstrual cycle. Many other functions have been found to be exerted by activin, including roles in cell proliferation, differentiation, apoptosis, metabolism, homeostasis, immune response, wound repair, and endocrine function. Conversely inhibin down regulates FSH synthesis and inhibits FSH secretion.Activins are nonglycosylated homodimers or heterodimers of various beta subunits (betaA, betaB, betaC, and betaE in mammals), while Inhibins are heterodimers of a unique alpha subunit and one of the beta subunits. Activin A is a widely expressed homodimer of two betaA chains. The betaA subunit can also heterodimerize with a betaB or betaC subunit to form Activin AB and Activin AC, respectively. The 14 kDa mature human betaA chain shares 100% amino acid sequence identity with bovine, feline, mouse, porcine, and rat betaA. |
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Activin A Recombinant Protein |
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| 96-912 | ProSci | 0.1 mg | 789.9 EUR |
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Description: Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activin enhances FSH biosynthesis and secretion, and participates in the regulation of the menstrual cycle. Many other functions have been found to be exerted by activin, including roles in cell proliferation, differentiation, apoptosis, metabolism, homeostasis, immune response, wound repair, and endocrine function. Conversely inhibin down regulates FSH synthesis and inhibits FSH secretion.Activins are nonglycosylated homodimers or heterodimers of various beta subunits (betaA, betaB, betaC, and betaE in mammals), while Inhibins are heterodimers of a unique alpha subunit and one of the beta subunits. Activin A is a widely expressed homodimer of two betaA chains. The betaA subunit can also heterodimerize with a betaB or betaC subunit to form Activin AB and Activin AC, respectively. The 14 kDa mature human betaA chain shares 100% amino acid sequence identity with bovine, feline, mouse, porcine, and rat betaA.Activin is produced in the gonads, pituitary gland, placenta, and other organs. The bioactivity of Activin A is regulated by a variety of mechanisms. In the ovarian follicle, activin increases FSH binding and FSH-induced aromatization; Activin is strongly expressed in wounded skin, and overexpression of activin in epidermis of transgenic mice improves wound healing and enhances scar formation; Activin also regulates the morphogenesis of branching organs such as the prostate, lung, and especially kidney. Activin A increased the expression level of type-I collagen suggesting that activin A acts as a potent activator of fibroblasts; Lack of activin during development results in neural developmental defects. |
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Activin A Recombinant Protein |
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| 40-643 | ProSci | 2 ug | 311.1 EUR |
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Description: Activin A is a TGF-β family member that exhibits a wide range of biological activities, including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in postmenopausal women have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin. Activin A binds to the two forms of activin receptor type I (Act RI-A and Act RI-B) and two forms of activin receptor type II (Act RII-A and Act RII-B). Activins are homodimers or heterodimers of different β subunits. They are produced as precursor proteins with an amino terminal propeptide that is cleaved to release the C-terminal bioactive ligand. Recombinant Human/Murine/Rat Activin A is a 26.0 kDa disulfide-linked homodimer of two βA chains, each containing 116 amino acid residues. |
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Activin A Recombinant Protein |
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| 40-212-0002mg | ProSci | 0.002 mg | 311.1 EUR |
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Description: Activin A is a TGF-β family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in post-menopausal woman have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, Follistatin. Human Activin A is a 26.0 kDa disulfide-linked homodimer of two β A chains, each containing 116 amino acid residues. |
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Activin A Recombinant Protein |
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| 40-212-001mg | ProSci | 0.01 mg | 437.1 EUR |
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Description: Activin A is a TGF-β family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in post-menopausal woman have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, Follistatin. Human Activin A is a 26.0 kDa disulfide-linked homodimer of two β A chains, each containing 116 amino acid residues. |
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Activin A Recombinant Protein |
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| 40-213-0002mg | ProSci | 0.002 mg | 311.1 EUR |
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Description: Activin A is a TGF-β family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in postmenopausal women have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin. Human Activin A is a 26.0 kDa disulfide-linked homodimer of two βA chains, each containing 116 amino acid residues. |
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Activin A Recombinant Protein |
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| 40-213-001mg | ProSci | 0.01 mg | 437.1 EUR |
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Description: Activin A is a TGF-β family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in postmenopausal women have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin. Human Activin A is a 26.0 kDa disulfide-linked homodimer of two βA chains, each containing 116 amino acid residues. |
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Activin-A Recombinant Protein |
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| 40-544 | ProSci | 0.01 mg | 481.2 EUR |
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Description: Activin A is a TGF-β family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in postmenopausal women have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin. Recombinant human Activin A is a 26.0 kDa disulfide-linked homodimer of two βA chains, each containing 116 amino acid residues. |
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Rat Activin A CLIA Kit |
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| MBS8426583-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Rat Activin A ELISA kit |
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| E02A0643-192T | BlueGene | 192 tests | 1524 EUR |
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Description: A competitive ELISA for quantitative measurement of Rat Activin A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rat Activin A ELISA kit |
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| E02A0643-48 | BlueGene | 1 plate of 48 wells | 624 EUR |
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Description: A competitive ELISA for quantitative measurement of Rat Activin A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rat Activin A ELISA kit |
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| E02A0643-96 | BlueGene | 1 plate of 96 wells | 822 EUR |
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Description: A competitive ELISA for quantitative measurement of Rat Activin A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rat Activin A ELISA kit |
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| E01A9037 | BlueGene | 96T | 700 EUR |
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Description: ELISA |
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Dog Activin A ELISA kit |
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| E08A0643-192T | BlueGene | 192 tests | 1524 EUR |
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Description: A competitive ELISA for quantitative measurement of Canine Activin A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Dog Activin A ELISA kit |
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| E08A0643-48 | BlueGene | 1 plate of 48 wells | 624 EUR |
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Description: A competitive ELISA for quantitative measurement of Canine Activin A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Dog Activin A ELISA kit |
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| E08A0643-96 | BlueGene | 1 plate of 96 wells | 822 EUR |
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Description: A competitive ELISA for quantitative measurement of Canine Activin A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Pig Activin A ELISA kit |
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| E07A0643-192T | BlueGene | 192 tests | 1524 EUR |
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Description: A competitive ELISA for quantitative measurement of Porcine Activin A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Pig Activin A ELISA kit |
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| E07A0643-48 | BlueGene | 1 plate of 48 wells | 624 EUR |
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Description: A competitive ELISA for quantitative measurement of Porcine Activin A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Pig Activin A ELISA kit |
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| E07A0643-96 | BlueGene | 1 plate of 96 wells | 822 EUR |
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Description: A competitive ELISA for quantitative measurement of Porcine Activin A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rat Activin A ELISA Kit |
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| EK5125 | SAB | 96 tests | 599 EUR |
Rat Activin A ELISA Kit |
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| 55R-1554 | Fitzgerald | 1 kit | 615 EUR |
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Description: ELISA kit for detection of Activin A in the research laboratory |
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Rat Activin A ELISA kit |
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| 55R-2102 | Fitzgerald | 96 tests | 808 EUR |
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Description: ELISA Kit for detection of Activin A in the research laboratory |
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Rat Activin A ELISA Kit |
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| CN-01617R1 | ChemNorm | 96T | 530.4 EUR |
Rat Activin A ELISA Kit |
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| CN-01617R2 | ChemNorm | 48T | 351.6 EUR |
Rat Activin A ELISA Kit |
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| MBS033358-10x96StripWells | MyBiosource | 10x96-Strip-Wells | 6725 EUR |
Rat Activin A ELISA Kit |
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| MBS033358-48StripWells | MyBiosource | 48-Strip-Wells | 550 EUR |
Rat Activin A ELISA Kit |
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| MBS033358-5x96StripWells | MyBiosource | 5x96-Strip-Wells | 3420 EUR |
Rat Activin A ELISA Kit |
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| MBS033358-96StripWells | MyBiosource | 96-Strip-Wells | 765 EUR |
Cat Activin A ELISA Kit |
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| MBS086494-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Rat Activin A ELISA Kit |
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| GWB-ZZD071 | GenWay Biotech | 1x96 well plate | Ask for price |
Rat Activin A ELISA Kit |
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| IRTATVAKT | Innovative research | each | 702 EUR |
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Description: Rat Activin A ELISA Kit |
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Rat Activin A ELISA kit |
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| LF-EK50541 | Abfrontier | 1×96T | 777.6 EUR |
Rat Activin A ELISA Kit |
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| MBS764521-10x96StripWells | MyBiosource | 10x96-Strip-Wells | 3900 EUR |
Rat Activin A ELISA Kit |
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| MBS764521-48StripWells | MyBiosource | 48-Strip-Wells | 340 EUR |
Rat Activin A ELISA Kit |
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| MBS764521-5x96StripWells | MyBiosource | 5x96-Strip-Wells | 2045 EUR |
Rat Activin A ELISA Kit |
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| MBS764521-96StripWells | MyBiosource | 96-Strip-Wells | 455 EUR |
Rat Activin A ELISA Kit |
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| MBS732005-10x96StripWells | MyBiosource | 10x96-Strip-Wells | 5685 EUR |
Rat Activin A ELISA Kit |
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| MBS732005-48StripWells | MyBiosource | 48-Strip-Wells | 485 EUR |
Rat Activin A ELISA Kit |
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| MBS732005-5x96StripWells | MyBiosource | 5x96-Strip-Wells | 3020 EUR |
Rat Activin A ELISA Kit |
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| MBS732005-96StripWells | MyBiosource | 96-Strip-Wells | 690 EUR |
Rat Activin A ELISA Kit |
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| MBS8421360-1Kit | MyBiosource | 1Kit | 755 EUR |
Rat Activin A ELISA Kit |
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| MBS8421360-5x1Kit | MyBiosource | 5x1Kit | 3455 EUR |
The Negotiator allows entry negotiation to greater than 600 biobanks from the BBMRI-ERIC Directory and different discovery providers similar to GBA/BBMRI-ERIC Locator or RD-Connect Finder. This article summarizes the rules that guided the design of the software, the terminology used and underlying knowledge mannequin, request workflows, authentication and authorization mechanism(s), and the mechanisms and monitoring processes to stimulate the specified habits of the sources: to successfully ship entry to organic materials and knowledge.