This assay employs the competitive inhibition enzyme immunoassay technique. The micro-plate provided in this kit has been pre-coated with 17-Hydroxyprogesterone (17-OHP) protein. Standards or samples are then added to the appropriate micro-plate wells with a biotin-conjugated antibody specific to 17-Hydroxyprogesterone (17-OHP). Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and… Continue reading
Category: profiling
Advancing human genetics research and drug discovery through exome sequencing of the UK Biobank
The UK Biobank Exome Sequencing Consortium (UKB-ESC) is a private-public partnership between the UK Biobank (UKB) and eight biopharmaceutical corporations that may full the sequencing of exomes for all ~500,000 UKB members. Here, we describe the early outcomes from ~200,000 UKB members and the options of this mission that enabled its success. The biopharmaceutical trade… Continue reading
Lifetime depression and age-related changes in body composition, cardiovascular function, grip strength and lung function: sex-specific analyses in the UK Biobank
Individuals with depression, on common, die prematurely, have excessive ranges of bodily comorbidities and might expertise accelerated organic ageing. A larger understanding of age-related changes in physiology might present novel organic insights that will assist inform methods to mitigate extra mortality in depression. We used generalised additive fashions to look at age-related changes in 15… Continue reading
Polygenic Scores and Parental Predictors: An Adult Height Study Based on the United Kingdom Biobank and the Framingham Heart Study
Human top is a polygenic trait, influenced by a lot of genomic loci. In the pre-genomic period, top prediction was primarily based largely on parental top. More latest predictions of human top have made nice strides by integrating genotypic knowledge from massive biobanks with improved statistical methods. Nevertheless, latest research haven’t leveraged parental top, an… Continue reading