FA58A Rabbit Polyclonal Antibody

Description: This gene encodes a membrane protein associated with the Golgi apparatus| which plays a crucial role in intracellular vesicular transport. The encoded protein is likely associated with the late (trans) Golgi compartments| which are involved in the delivery of secretory and membrane proteins to the endosome| lysosome or the plasma membrane. Alternative splicing results in multiple transcript variants.

Description: This gene encodes a membrane protein associated with the Golgi apparatus| which plays a crucial role in intracellular vesicular transport. The encoded protein is likely associated with the late (trans) Golgi compartments| which are involved in the delivery of secretory and membrane proteins to the endosome| lysosome or the plasma membrane. Alternative splicing results in multiple transcript variants.

Description: This gene encodes a membrane protein associated with the Golgi apparatus| which plays a crucial role in intracellular vesicular transport. The encoded protein is likely associated with the late (trans) Golgi compartments| which are involved in the delivery of secretory and membrane proteins to the endosome| lysosome or the plasma membrane. Alternative splicing results in multiple transcript variants.

Description: disease:Defects in F8 are the cause of hemophilia A (HEMA)

Description: disease:Defects in F8 are the cause of hemophilia A (HEMA)

Description: disease:Defects in F8 are the cause of hemophilia A (HEMA)

Description: disease:Defects in F8 are the cause of hemophilia A (HEMA)

Description: disease:Defects in F8 are the cause of hemophilia A (HEMA)

Description: disease:Defects in F8 are the cause of hemophilia A (HEMA)

Description: disease:Defects in F8 are the cause of hemophilia A (HEMA)

Description: disease:Defects in F8 are the cause of hemophilia A (HEMA)

Description: disease:Defects in F8 are the cause of hemophilia A (HEMA)

Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Description: This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen| which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI| an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains| resulting in activated factor XIa| a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome| a blood coagulation abnormality.

Description: This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen| which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI| an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains| resulting in activated factor XIa| a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome| a blood coagulation abnormality.

Description: This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen| which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI| an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains| resulting in activated factor XIa| a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome| a blood coagulation abnormality.

Description: This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen| which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI| an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains| resulting in activated factor XIa| a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome| a blood coagulation abnormality.

Description: This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen| which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI| an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains| resulting in activated factor XIa| a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome| a blood coagulation abnormality.

Description: This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen| which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI| an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains| resulting in activated factor XIa| a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome| a blood coagulation abnormality.

Description: This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen| which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI| an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains| resulting in activated factor XIa| a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome| a blood coagulation abnormality.

Description: This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen| which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI| an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains| resulting in activated factor XIa| a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome| a blood coagulation abnormality.

Description: This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen| which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI| an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains| resulting in activated factor XIa| a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome| a blood coagulation abnormality.

Description: This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen| which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI| an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains| resulting in activated factor XIa| a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome| a blood coagulation abnormality.

Description: This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen| which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI| an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains| resulting in activated factor XIa| a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome| a blood coagulation abnormality.

Description: This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen| which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI| an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains| resulting in activated factor XIa| a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome| a blood coagulation abnormality.

Description: Catalytic activity:Selective cleavage of Arg-|-Thr and then Arg-|-Ile bonds in prothrombin to form thrombin.|Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va| calcium and phospholipid during blood clotting.|online information:Factor X entry|PTM:N- and O-glycosylated.|PTM:The activation peptide is cleaved by factor IXa (in the intrinsic pathway)| or by factor VIIa (in the extrinsic pathway).|PTM:The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.|PTM:The vitamin K-dependent| enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium.|Belongs to the peptidase S1 family.|Contains 1 Gla (gamma-carboxy-glutamate) domain.|Contains 1 peptidase S1 domain.|Contains 2 EGF-like domains.|subunit:The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds.|tissue specificity:Plasma; synthesized in the liver.|

Description: Catalytic activity:Selective cleavage of Arg-|-Thr and then Arg-|-Ile bonds in prothrombin to form thrombin.|Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va| calcium and phospholipid during blood clotting.|online information:Factor X entry|PTM:N- and O-glycosylated.|PTM:The activation peptide is cleaved by factor IXa (in the intrinsic pathway)| or by factor VIIa (in the extrinsic pathway).|PTM:The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.|PTM:The vitamin K-dependent| enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium.|Belongs to the peptidase S1 family.|Contains 1 Gla (gamma-carboxy-glutamate) domain.|Contains 1 peptidase S1 domain.|Contains 2 EGF-like domains.|subunit:The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds.|tissue specificity:Plasma; synthesized in the liver.|

Description: Catalytic activity:Selective cleavage of Arg-|-Thr and then Arg-|-Ile bonds in prothrombin to form thrombin.|Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va| calcium and phospholipid during blood clotting.|online information:Factor X entry|PTM:N- and O-glycosylated.|PTM:The activation peptide is cleaved by factor IXa (in the intrinsic pathway)| or by factor VIIa (in the extrinsic pathway).|PTM:The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.|PTM:The vitamin K-dependent| enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium.|Belongs to the peptidase S1 family.|Contains 1 Gla (gamma-carboxy-glutamate) domain.|Contains 1 peptidase S1 domain.|Contains 2 EGF-like domains.|subunit:The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds.|tissue specificity:Plasma; synthesized in the liver.|

Description: A Rabbit Polyclonal antibody against F19A1 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

Description: A Rabbit Polyclonal antibody against F19A1 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

Description: A Rabbit Polyclonal antibody against F19A2 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

Description: A Rabbit Polyclonal antibody against F19A2 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

Description: A Rabbit Polyclonal antibody against F19A5 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

Description: A Rabbit Polyclonal antibody against F19A5 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

Description: Antibodies against the protein encoded by this gene were found only in plasma from cancer patients. While it may be a target for immunotherapy| the function of this gene is unknown.

Description: Antibodies against the protein encoded by this gene were found only in plasma from cancer patients. While it may be a target for immunotherapy| the function of this gene is unknown.

Description: Antibodies against the protein encoded by this gene were found only in plasma from cancer patients. While it may be a target for immunotherapy| the function of this gene is unknown.

Description: This gene encodes a member of the FAM69 family of cysteine-rich type II transmembrane proteins. These proteins localize to the endoplasmic reticulum but their specific functions are unknown.

Description: This gene encodes a member of the FAM69 family of cysteine-rich type II transmembrane proteins. These proteins localize to the endoplasmic reticulum but their specific functions are unknown.

Description: This gene encodes a member of the FAM69 family of cysteine-rich type II transmembrane proteins. These proteins localize to the endoplasmic reticulum but their specific functions are unknown.